Hydrotalcite-like Materials as Catalyst for the Conjugate Addition of Amines to Electron Deficient Alkenes

›› 2009, Vol. 17 ›› Issue (5): 875-878.

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Hydrotalcite-like Materials as Catalyst for the Conjugate Addition of Amines to Electron Deficient Alkenes

CHEN Lu¹, ZHU Juan¹, WANG Jian¹, WU Haihong¹, YANG Jianguo^1,2

1. Key Laboratory of Green Chemistry and Chemical Process, Department of Chemistry, East China Normal University, Shanghai 200062, China;
2. Energy Institue, Department of Materials Science and Engineering, Pennsylvania State University, University Park, PA 16802, USA

Received:2009-03-05 Revised:2009-07-28 Online:2009-10-28 Published:2009-10-28
Supported by:
Supported by the National Key Project of Scientific and Technical Supporting Programs Funded by Ministry of Science & Technology of China (2006BAE03B06);Shanghai Leading Academic Discipline Project (B409);Shanghai International Cooperation of Science and Technology Project (06SR07101)

Hydrotalcite-like Materials as Catalyst for the Conjugate Addition of Amines to Electron Deficient Alkenes

陈露¹, 朱娟¹, 王箭¹, 吴海虹¹, 杨建国^1,2

1. Key Laboratory of Green Chemistry and Chemical Process, Department of Chemistry, East China Normal University, Shanghai 200062, China;
2. Energy Institue, Department of Materials Science and Engineering, Pennsylvania State University, University Park, PA 16802, USA

通讯作者: YANG Jianguo,E-mail:jgyang@chem.ecnu.edu.cn;jzy2@psu.edu
基金资助:
Supported by the National Key Project of Scientific and Technical Supporting Programs Funded by Ministry of Science & Technology of China (2006BAE03B06);Shanghai Leading Academic Discipline Project (B409);Shanghai International Cooperation of Science and Technology Project (06SR07101)

Abstract

Abstract: The novel efficient procedure has been developed for the conjugate addition of amines to electron deficient alkenes.A series of hydrotalcite-like materials were synthesized as catalyst for the conjugate addition of amines and alkenes.After optimizing the reaction conditions,ZnAl-LDHs (3:1) was chosen as the best catalyst for the reaction.The results showed that the catalyst worked very well for the conjugate addition of amines to electron deficient alkenes with the excellent yields in several minutes.Operational simplicity,no solvent,low cost of the catalyst,high yields,reusability,excellent chemoselectivity,wide applicability are the key features of this method.

Key words: hydrotalcite-like material, conjugate addition, chemoselectivity, solvent-free synthesis

摘要： The novel efficient procedure has been developed for the conjugate addition of amines to electron deficient alkenes.A series of hydrotalcite-like materials were synthesized as catalyst for the conjugate addition of amines and alkenes.After optimizing the reaction conditions,ZnAl-LDHs (3:1) was chosen as the best catalyst for the reaction.The results showed that the catalyst worked very well for the conjugate addition of amines to electron deficient alkenes with the excellent yields in several minutes.Operational simplicity,no solvent,low cost of the catalyst,high yields,reusability,excellent chemoselectivity,wide applicability are the key features of this method.

关键词: hydrotalcite-like material, conjugate addition, chemoselectivity, solvent-free synthesis

CHEN Lu, ZHU Juan, WANG Jian, WU Haihong, YANG Jianguo, Shanghai. Hydrotalcite-like Materials as Catalyst for the Conjugate Addition of Amines to Electron Deficient Alkenes[J]. , 2009, 17(5): 875-878.

陈露, 朱娟, 王箭, 吴海虹, 杨建国. Hydrotalcite-like Materials as Catalyst for the Conjugate Addition of Amines to Electron Deficient Alkenes[J]. , 2009, 17(5): 875-878.

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Hydrotalcite-like Materials as Catalyst for the Conjugate Addition of Amines to Electron Deficient Alkenes

Hydrotalcite-like Materials as Catalyst for the Conjugate Addition of Amines to Electron Deficient Alkenes

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