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SCI和EI收录∣中国化工学会会刊
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Table of Content
28 December 2002, Volume 10 Issue 6
    SELECTED PAPERS FROM……
    Studies on a New Random Packing-Plum Flower Mini Ring
    FEI Weiyang, SUN Lanyi, GUO Qingfeng
    2002, 10(6):  631-634.  doi:
    Abstract ( )   PDF (1050KB) ( )  
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    The hydrodynamics and mass transfer of Plum Flower Mini Ring (PFMR), Pall Ring and Intalox
    Saddle were studied in a 600 mm diameter column with air-oxygen-water system over a wide
    range of liquid loads. It was shown fiom the experiments that PFMR had much lower
    resistance, larger throughput and higher mass transfer efficiency than Pall Ring and
    Intalox Saddle. It was clear from the comparison that existing equations could not predict
    the performance of packings very well at high liquid loads. Therefore, new semi-empirical
    equations of pressure drop, flooding gas velocity and height of transfer unit (HTU) were
    proposed based on the experimental data.
    Performance of Structured Packing in High Pressure Distillation
    ZHANG Peng, LIU Chunjiang, WANG Lidong, TANG Zhongli, YU Guocong
    2002, 10(6):  635-638.  doi:
    Abstract ( )   PDF (969KB) ( )  
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    Performance of Mellapak 250Y and 350Y corrugated structured packing in distillation
    applications at pressures rangingfrom 0.3 to 2.0MPa is analysed by using HTU-NTU method.
    These data are obtained in a distillation column with 0.15 m diameter op-erated with n-
    butane/n-pentane system at total reflux. In considering the axial backmixing effects, the
    height of an overall gas phasetransfer unit, HTUOG, is divided into two parts. One part
    represents the height of an overall gas phase transfer unit, withoutbackmixing,designated
    asHTU*OG, and the other part, designated as the height ofa backmixing unit (HBUo), accounts
    for the backmixing effects.The HTUOG is evaluated from the measured concentration profile
    of n-butane in liquid phase. The HBUo obtained experimentally iscorrelated in terms of the
    properties of the materials being separated and the equivalent diameter of the structured
    packing. Our resultshows that HBUo varies from 0.12 to 0.34 m as pressure increases from
    1.0 to 1.9 MPa. It indicates that the overall efficiency of thestructured packing decreases
    gradually at high pressure, as a result of the vapor backmixing.
    Adsorption of Diblock Copolymers from Non-selective Solvent: Comparison Between Scheutjens
    -Fleer Theory and Monte Carlo Simulation
    GUO Lian, YE Ruqiang, YING Changming, LIU Honglai, HU Ying
    2002, 10(6):  639-643.  doi:
    Abstract ( )   PDF (1525KB) ( )  
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    Systematic comparison between computer simulation results and those predicted by
    Scheutjens-Fleer (SF) self-consistent-field theory is presented for the adsorption of
    diblock copolymers from a non-selective solvent on attractive surface. It is shown that
    although SF is a mean-field theory, it can qualitatively describe the adsorption phenomena
    of diblock copolymers. However, systematic discrepancy between the theory and simulation
    still exists. The approximations inherited in the mean-field theory such as random mixing
    inside a layer and the allowance of direct back folding may be responsible to those
    deviations.
    Ethane Adsorption in Single Walled Carbon Nanotube by Density Functional Theory
    ZHANG Xianren
    2002, 10(6):  644-649.  doi:
    Abstract ( )   PDF (1632KB) ( )  
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    Density functional theory (DFT) is used to calculate adsorption of ethane molecules in
    single walled carbon nanotubes. A compari-son of DFT calculations and grand canonical
    ensemble Monte Carlo (GCMC) simulations is made first and the two methods are in good
    agree-ment. Adsorption isotherms and structures of ethane molecules inside the tubes have
    been studied by DFT for the nanotubes of diameters 0.954,2.719 and 4.077 nm at 157 K and
    ambient temperature, 300 K. By using the grand potential, the positions of phase
    transitions are exactly lo-cated, and the effect of temperature and tube diameter on phase
    transitions and adsorption is discussed. We found that lowering temperature andincreasing
    the pore size of several nanometer is preferable for the ethane adsorption when temperature
    is in the range of 157 K-300 K and op-erating pressure reaches several MPa. Layering
    transitions and capillary condensations are observed at 157 K in two larger pore
    diameters,while these phase transitions disappear or the hysteres is loops become very
    narrow at 300 K.
    Adsorption of Heavy Metal Ions by Adsorbent from Waste Mycelium Chitin
    SU Haijia, WANG Lijuan, TAN Tianwei
    2002, 10(6):  650-652.  doi:
    Abstract ( )   PDF (907KB) ( )  
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    The adsorption properties of chitin adsorbent from mycelium of fermentation industries for
    the removal of heavy metal ions werestudied. The result shows that the chitin adsorbent has
    high adsorption capacity for many heavy metal ions and Ni2+ in citric acid. The influenceof
    pH was significant: When pH is higher than 4.0, the high adsorption capacity is obtained,
    otherwise H+ ion inhibits the adsorption of heavymetal ions. The comparison of the chitin
    adsorbent with some other commercial adsorbents was made, in which that the adsorption
    behavior ofchitin adsorbent is close to that of commercial cation exchange adsorbents, and
    its cost is much lower than those commercial adsorbents.
    An Experimental Simulation of Load-Leveling Through Adsorption for Natural Gas Pipeline
    System
    ZHOU Li, WANG Yilin, CHEN Haihua, ZHOU Yaping
    2002, 10(6):  653-656.  doi:
    Abstract ( )   PDF (1201KB) ( )  
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    A load-leveling method through adsorption was presented to adjust the supply quantity
    according to the consumption rate of naturalgas with time. An experimental simulation set
    up was designed and used to test the load-leveling function for a real pipeline system. A
    storagetank filled with activated carbon together with a filter constitutes the major part
    of the load-leveling facility. Pressure and temperature of thesystem, as well as the reai
    gas output of the storage tank were recorded. It is proven that load-leveling by adsorption
    is technically feasible evenfor low pipeline pressure of natural gas supply system.
    Vapor-Liquid Equilibrium of Toluene-Polycyclic Aromatic Hydrocarbon System in Sub-and
    Supercritical State
    Cheol-Joong KIM, Dong-Bok WON, Kyu-Jin HAN, So-Jin PARK
    2002, 10(6):  657-660.  doi:
    Abstract ( )   PDF (1266KB) ( )  
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    The phase behaviors of toluene/polycyclic aromatic hydrocarbon mixture systems were
    investigated with a continuous-flow typeapparatus at 573.2, 598.2, 623.2 and 648.2 K, while
    the pressure changed from I to 5MPa. The pseudo-binary phase behaviors were predictedwith
    the Peng-Robinson equation of state with interaction parameters between toluene and pseudo
    -components considered. The phase diagramsof the system have been classified following the
    category of phase boundary diagram models. The extraction selectivity and efficiency of
    tolue-ne as a solvent was discussed by comparing with that of hexane. The prediction model
    for selectivity was also suggest, ed.
    Correlation of Critical Loci for Water-Hydrocarbon Binary Systems by EOS Based on the
    Multi-Fluid Nonrandom Lattice Theory
    HunYong SHIN, Hwayong KIM, Ki-Pung YOO, ChulSoo LEE, Yoshio IWAI, Yasuhiko ARAI
    2002, 10(6):  661-665.  doi:
    Abstract ( )   PDF (1398KB) ( )  
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    Quantitative representation of complicated behavior of fluid mixtures in the critical
    region by any of equation-of-state theories re-mains as a difficult thermodynamic topics to
    date. In the present work, a computational efforts were made for representing various types
    ofcritical loci of binary water with hydrocarbon systems showing Type Ⅱ and Type Ⅲ phase
    behavior by an elementary equation of state [calledmulti-fluid nonrandom lattice fluid EOS
    (MF-NLF EOS)] based on the lattice statistical mechanical theory. The model EOS requires
    two mo-lecular parameters which representing molecular size and interaction energy for a
    pure component end single adjustable interaction energyparameter for binary mixtures.
    Critical temperature and pressure data were used to obtain molecular size parameter and
    vapor pressure datawere used to obtain interaction energy parameter. The MF-NLF EOS model
    adapted in the present study correlated quantitatively well the criti-cal loci of various
    binary water with hydrocarbon systems.
    Measurement and Correlation of Partition Coefficients of Baicalin in EOPO/Salt Aqueous Two
    -Phase Systems
    LI Wei, ZHU Ziqiang
    2002, 10(6):  666-669.  doi:
    Abstract ( )   PDF (1130KB) ( )  
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    The partition coefficients of baicalin were measured in ethylene oxide and propylene oxide
    (EOPO)/salt aqueous two-phase systemsat 298.15K. It was found that most of baicalin
    partitioned into EOPO-rich phase. The partition coefficients of baicalin varied from 10 to
    120.The effect of various factors, including tie-line length, salt composition, molecular
    weight of EOPO, and solution pH, on the partition behaviorwas investigated in EOPO/salt
    systems. Furthermore the partition coefficients of baicalin were correlated using the
    modified Diamond-Hsumodel. Good agreement with experimental data is obtained. The average
    relative deviations are less than 5.0%.
    Phase Behavior and Structural Transitions in Sodium Dodecyl Sulfonate Microemulsions
    YANG Gensheng, SHI Jiehua, LI Jinghua, WANG Pu, YAO Shanjing
    2002, 10(6):  670-672.  doi:
    Abstract ( )   PDF (1034KB) ( )  
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    The forming mechanism ofmicroemulsion of sodium dodecyl sulfonate, alcohols, water and
    isooctane was studied, with particular emphasis on the effect of molecular weight and
    concentration of alcohols. Phase diagram of the four components, alcohol,sodium dodecyl
    sulfonate, water and isooctane, was used as a means of study, through which the
    microemulsion regions were determined. Phase diagram of sodium dodecyl sulfonate/n-
    pentanol/isooctane/water system at km, = 2 (km, = Wn-pentanol / WsDs ) is presented.The
    variation of conductivities of different microemulsion samples with water was measured.
    From the conductivities we investigated a change in structure from water droplets in oil
    (W/O) at low water content to liquid crystal at intermediate water content and a struc ture
    ofoil droplets in water (O/W) at high water content.
    Separation of Erucic Acid from Rape-Seed Oil Using Supercritical Carbon Dioxide with
    Entrainer
    YUN Zhi, QIAN Renyuan, SHAO Rong, YANG Mei, SHI Meiren
    2002, 10(6):  673-676.  doi:
    Abstract ( )   PDF (954KB) ( )  
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    Separation of erucic acid from rape-seed oil using supercritical carbon dioxide with
    entrainer was carried on a pilot column with an inner diameter 14 mm and an effective total
    height 2.2 m. Experiments were focused on the effects of entrainers, i.e. acetone,ethanol
    and ethyl acetate, on the extraction. It is showed that entrainers made selectivity lower,
    but separation time shorter.
    Extraction of Caprolactam from Aqueous Ammonium Sulfate Solution in Pulsed Packed Column
    Using 250Y Mellapak Packings
    XIE Fangyou, ZHU Mingqiao, LIU Jianqing, HE Chaohong
    2002, 10(6):  677-680.  doi:
    Abstract ( )   PDF (1060KB) ( )  
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    Liquid-liquid equilibrium (LLE) data of water-caprolactam-benzene-(NH4)2SO4 system at 303 K
    were measured for extraction of caprolactam from aqueous ammonium sulfate solution. The
    influence of fluid flow rate, pulsation intensity on flooding velocity and mass transfer
    was studied for extraction of caprolactam from ammonium sulfate solution in a laboratory
    pulsed packed column. The flooding velocities and overall apparent height of a transfer
    unit were given under various operation conditions. An industrial column developed based on
    above study is operated well. The scale-up effect is discussed.
    Comparative Optical Separation of Racemic Ibuprofen by Using Chiral Stationary Phase
    Dalkeun PARK, Joong Kee LEE, So-Young KIM, Taeho SONG, Sung-Sup SUH
    2002, 10(6):  681-685.  doi:
    Abstract ( )   PDF (1562KB) ( )  
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    Ibuprofen is widely used as a non-steroidal anti-inflammatory drug and produced as racemic
    mixture. Its pharmacological activity resides only in S-(+)-enantiomer, and R-(-)-
    enantiomer is not only inactive but also has many side effects. Thus it is necessary to
    separate Renanfiomer from racemic ibuprofen. We studied optical separation of racemic
    Ibuprofen with chiral high performance liquid chromatography (HPLC). Out of three different
    chiral stationary phases, which were selected on the basis of structure and availability,
    two were found to be effective. There was optimum eluent composition for each stationary
    phase for good resolution in optical separation. Resolution decreased with increase of
    eluent flow rate, but effect of injection volume on resolution was insignificant at high
    eluent flow rate.
    Primary Purification of Co-expressed Soluble and Insoluble Alpha-interferon 2b from
    Recombinant E.coli
    XU Zhinan, CEN Peilin
    2002, 10(6):  686-689.  doi:
    Abstract ( )   PDF (1106KB) ( )  
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    Alpha-interferon 2b (IFN 2b) was produced both in soluble and insoluble forms from
    recombinant E. coli. The dissolution of the expressed IFN 2b in inclusion body was carried
    out and it was found that the optimal condition to dissolve the expressed protein was 7
    mol. L-1guanidininm salt solution at pH 3.0. The resultant solution was diluted 20 times
    using pH 6.0 buffer to ref+ld the protein correctly. The cation exchange column was
    employed to purify both refolded and soluble IFN 2b. For soluble IFN sample, high IFN 2b
    recovery yield (92.1%) with 91.7% purity was obtained in the eluate. However, for refolded
    IFN sample, only 72.7% ofIFN 2b was recovered with relatively low purity (56.8%) by cation
    exchange chromatography. Although the expression level of insoluble IFN was higher than
    that of co-expressed soluble IFN in this recombinant E.coli cells, the productivity of
    bioactive IFN 2b was higher with soluble expressed IFN after primary purification process.
    Soluble expression of foreign proteins in recombinant bacteria might be an alternative
    strategy for efficient production of heterogeneous proteins due to high bioactivity and
    simple downstream protein purification process.
    The Development of Gel Media and Columns for Large-Scale Chromatography of Proteins, a
    Historical Review
    Jan-Christer Janson
    2002, 10(6):  690-695.  doi:
    Abstract ( )   PDF (2290KB) ( )  
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    The first dedicated protein chromatography media were introduced during the 1950s and
    1960s. There was an early awareness of the possibility of using these for production
    applications within the biopharmaceutical industry. However, the crucial limitation was the
    fact that those media that were most compatible with proteins lent themselves less
    favourably to scaling-up. The problems were primarily physical. Thus the fibrous cellulose
    media showed bed cracking tendencies and the bead shaped polyacrylamide, dextran, and
    agarose gel media, then available,were too soft to stand the hydrodynamic forces acting in
    large columns, leading to bed compaction and increased pressure drop. At the time, the best
    solution to the latter problem, after a number of intermediary solutions were tried, was
    the introduction of the stacked column concept in which several short column segments were
    connected by small bore tubing, thus reducing the force acting on the particles in each bed
    compartment. However, the ultimate remedy, the introduction of chromatographic matrices
    that combine the desired features of adequate rigidity,macroporosity, biocompatibility,
    chemical stability (for CIP and SIP) and derivatizability, did not occur until the middle
    of the 1980s when adequately cross-linked agarose gel media such as Sepharose(R) Fast Flow
    were made available. The paper also recognizes the many attempts made during the past 50
    years to develop continous chromatography columns. Most of the designs are based on an
    annular bed or on an array of annularly arranged parallel columns continuously fed with
    samples in a cyclic manner. The introduction of media and columns for expanded bed
    adsorption followed a demand for fewer purification steps and shorter process times. In
    recent years, columns have been introduced that allow packing and repacking without needing
    to open the column. The review provides an historical account of the developments that have
    led to the present state-of-the-art both regarding large diameter columns and gel media
    intended for industrial applications of protein chromatography and also discusses the
    current trends that point to possible future applications.
    RESEARCH PAPERS
    Hydrodynamics and Mass Transfer Performance in Supercritical Fluid Extraction Columns
    SHI Bingjie, ZHANG Weidong, ZHANG Zeting, YU Enping
    2002, 10(6):  696-700.  doi:
    Abstract ( )   PDF (1160KB) ( )  
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    New models for describing hydrodynamics and mass transfer performance in supercritical
    fluid extraction columns were proposed.Those models were proved by experimental data, which
    were obtained in supercritical fluid extraction packed column, spray column and sieve tray
    column respectively. The inner diameter of those columns are φ25 mm. These experimental
    systems include supercritical carbon dioxide-isopropanol-water and supercritical carbon
    dioxide-ethanol-water, in which supercritical carbon dioxide was dispersed phase, and
    another was continuous phase. The extraction processes were operated with continuous
    conntercurrent flow. The predicted values are agreed well with ex-perimental data.
    Matrix Expression of the Orthogonal Wavelet (Packets) Transform
    DU Hongbin, TENG Hu, YAO Pingjing
    2002, 10(6):  701-705.  doi:
    Abstract ( )   PDF (1226KB) ( )  
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    Matrix expression of finite orthogonal wavelet transform of finite impulse response signal
    is more valuable for theoretical analysis and understanding. However, clear deduction for
    matrix expression has not been provided yet. In this paper, the formulation to generate the
    related matrix is put forward and the theorem on the orthogonality of this matrix proved.
    This effort deploys a basis for more deeper and wider applications in chemical processes.
    Prediction of Phase Behavior for Styrene/CO2/Polystyrene Mixtures
    WU Jialong, PAN Qinmin, G. L. Rempel
    2002, 10(6):  706-710.  doi:
    Abstract ( )   PDF (750KB) ( )  
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    A lattice fluid model, Sanchez-Lacombe equation, is used to predict the phase behavior for
    a styrene/CO2/polystyrene ternary system. The binary parameters involved in the equation
    were optimized using experimental data. Phase diagrams and the distribution coefficients of
    styrene between polymer phase and fluid phase are obtained over a wide range of pressure,
    temperature and composition. The analysis of ternary phase diagrams indicates that this
    system at relatively high pressure or low temperature may display two-phase equilibrium,
    and at low pressures or high temperatures three-phase equilibrium may appear. The
    distribution coefficients of styrene between the fluid phase and the polymer phase increase
    asymptotically to unity when the concentration of styrene increases. The results provide
    thermodynamic knowledge for further exploitation of supercritical carbon dioxide assisted
    devolatilization and impregnation.
    Method for Incorporation of Controllability in Heat Exchanger Network Synthesis by
    Integrating Mathematical Programming and Knowledge Engineering
    LI Zhihong
    2002, 10(6):  711-716.  doi:
    Abstract ( )   PDF (1778KB) ( )  
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    A method for incorporation of controlling the heat exchanger networks with or without
    splits is proposed by integrating mathematical programming and knowledge engineering. The
    simultaneous optimal mathematical model is established. This method can be practically used
    in the integration of large-scale heat exchanger networks, not only to synthesize
    automatically but also to satisfy the requirement of structural controllability with more
    objective human intervention.
    RESEARCH NOTES
    A New Method for Isolating and Purifying Natural Drug Taxol
    XIAO Jian, HAN Jinyu, MA Peisheng
    2002, 10(6):  717-719.  doi:
    Abstract ( )   PDF (876KB) ( )  
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    A pharmacological interaction target (PIT) method for solving the difficult problem in the
    separation of taxol from cephalonmanine was proposed. A two-phase extraction technique was
    used to carry out the PIT separation process. The effects of buffer, temperature and
    protein on the separation were investigated. Feasible disassembly conditions were also
    discussed. The final purity of taxol can reach 95% or higher.
    Comparison of Frontal Analysis and Elution-Curve Method for Determining Adsorption
    Isotherms
    Ju-Weon LEE, Kyung Ho ROW
    2002, 10(6):  720-722.  doi:
    Abstract ( )   PDF (68KB) ( )  
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    Adsorption isotherm is the most fundamental information related to chromatography. To
    calculate the parameters of Langmuir adsorption isotherm of thymidine, frontal analysis
    (FA) and elution-curve method (ECM) were adopted in reversed-phase high performance liguid
    chromatography (RP-HPLC). In FA, the concentration of stationary phase was measured from
    the elution curves and the isotherm was determined by regression analysis, while the
    parameters by ECM were obtained by parameter optimization. The adsorption isotherms of
    thymidine from the two methods were very similar. The superiority of ECM over FA was that
    the consumption of sample was less and only one or two injections of sample were required.
    Characterization of Crude Cellulase from Trichoderma reesei and Purification of Cellulase
    YAO Shanjing, GUAN Yixin, YU Lihua
    2002, 10(6):  723-725.  doi:
    Abstract ( )   PDF (857KB) ( )  
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    The gel filtration was carried out for purification of cellulase. The influences of
    chromatographic parameters on the resolution were studied to determine the optimal
    conditions for purification. The purified endoglucanase was obtained by gel filtration by
    Superdex 75 prep grade with an activity recovery of 92.8% and the purification factor 4.2.
    The sample volume should be below 6 % of the column bed volume and the column bed height L
    ≥ 12.0 cm. The optimum catalysis temperature and pH for the enzyme were 55 ℃ and 4.5-5.0,
    respectively. The cellulase was stable at pH ranging from 4.0 to 6.0 and temperature below
    60 ℃.