A convenient method for the determination of molecular weight cut-off of ultrafiltration membranes

doi:10.1016/j.cjche.2016.06.014

›› 2017, Vol. 25 ›› Issue (1): 62-67.DOI: 10.1016/j.cjche.2016.06.014

• Separation Science and Engineering • Previous Articles Next Articles

A convenient method for the determination of molecular weight cut-off of ultrafiltration membranes

Cunyu Li^1,2, Yun Ma¹, Hongyang Li¹, Guoping Peng^1,2

1 Pharmacy College, Nanjing University of Chinese Medicine, Nanjing 210023, China;
2 Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, Nanjing 210023, China

Received:2016-04-15 Revised:2016-06-29 Online:2017-02-15 Published:2017-01-28
Supported by:
Supported by the National Natural Science Foundation of China (No. 81503258, No. 81373980), Youth Natural Science Foundation of Jiangsu Province (No. BK20151005), Science and Technology Project of Jiangsu Traditional Chinese Medicine Administration (No. YB2015009).

A convenient method for the determination of molecular weight cut-off of ultrafiltration membranes

Cunyu Li^1,2, Yun Ma¹, Hongyang Li¹, Guoping Peng^1,2

1 Pharmacy College, Nanjing University of Chinese Medicine, Nanjing 210023, China;
2 Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, Nanjing 210023, China

通讯作者: Guoping Peng,E-mail address:guopingpeng@126.com
基金资助:
Supported by the National Natural Science Foundation of China (No. 81503258, No. 81373980), Youth Natural Science Foundation of Jiangsu Province (No. BK20151005), Science and Technology Project of Jiangsu Traditional Chinese Medicine Administration (No. YB2015009).

Abstract

Abstract: With the rapid increase of water contamination, membrane separation technology and their corresponding molecular weight cut-off (MWCO) evaluation method become more necessary. In this study, Panax notoginseng saponins was used as a new standard marker to determinate ultrafiltration (UF) membrane MWCOs, series of Millipore membranes were selected as control group to analyze and calculate the relationship between retention rate and MWCOs with exponential or logarithmic equation. A new and convenient method was provided for determining the membrane MWCO by modeling analysis retention rate with MWCOs, and the regression coefficients ≥0.990. The feasibility and practicability of established method was verified by different manufactures' membrane and dextrans. In the detection progress, as the main ingredient of Panax notoginseng saponins, Notoginsenoside R₁, Ginsenoside Rg₁, Ginsenoside Rb₁ and Ginsenoside Rd with different surface activity, the MWCO range of UF membranes can be divided into two zones mainly due to the retention rate difference among Notoginsenoside R₁, Ginsenoside Rg₁, Ginsenoside Rb₁ and Ginsenoside Rd. Zone I, 1000-10000; and Zone II, 10000-100000. Thus, the new method would be helpful to improve the applicability of UF membrane in separation technology.

Key words: Ultrafiltration membrane, Molecular weight cut-off

摘要： With the rapid increase of water contamination, membrane separation technology and their corresponding molecular weight cut-off (MWCO) evaluation method become more necessary. In this study, Panax notoginseng saponins was used as a new standard marker to determinate ultrafiltration (UF) membrane MWCOs, series of Millipore membranes were selected as control group to analyze and calculate the relationship between retention rate and MWCOs with exponential or logarithmic equation. A new and convenient method was provided for determining the membrane MWCO by modeling analysis retention rate with MWCOs, and the regression coefficients ≥0.990. The feasibility and practicability of established method was verified by different manufactures' membrane and dextrans. In the detection progress, as the main ingredient of Panax notoginseng saponins, Notoginsenoside R₁, Ginsenoside Rg₁, Ginsenoside Rb₁ and Ginsenoside Rd with different surface activity, the MWCO range of UF membranes can be divided into two zones mainly due to the retention rate difference among Notoginsenoside R₁, Ginsenoside Rg₁, Ginsenoside Rb₁ and Ginsenoside Rd. Zone I, 1000-10000; and Zone II, 10000-100000. Thus, the new method would be helpful to improve the applicability of UF membrane in separation technology.

关键词: Ultrafiltration membrane, Molecular weight cut-off

Cunyu Li, Yun Ma, Hongyang Li, Guoping Peng. A convenient method for the determination of molecular weight cut-off of ultrafiltration membranes[J]. , 2017, 25(1): 62-67.

References

[1] Y. Zhou, Z.L. Dai, D. Zhai, C.J. Gao, Surface modification of polypiperazine-amide membrane by self-assembled method for dye wastewater treatment, Chin. J. Chem. Eng. 23(6) (2015) 912-918.
[2] H.Q. Zhang, Z.X. Zhong, W.X. Li, W.H. Xing, W.Q. Jin, River water purification via a coagulation-porous ceramic membrane hybrid process, Chin. J. Chem. Eng. 22(1) (2014) 113-119.
[3] J. Wang, J. Liu, J. Lu, Z. Cui, Isolation and purification of superoxide dismutase from garlic using two-stage ultrafiltration, J. Membr. Sci. 352(2010) 231-238.
[4] J. Ren, Z. Li, F.S. Wong, A new method for the prediction of pore size distribution and MWCO of ultrafiltration membranes, J. Membr. Sci. 279(2006) 558-569.
[5] H. de Balmann, R. Nobrege, The deformation of dextran moleculares. Causes and consequences in ultrafiltration, J. Membr. Sci. 40(1989) 311-327.
[6] G. Schock, A. Miquel, R. Birkenberger, Characteristization of ultrafiltration membranes:cut-off determination by gel permeation chromatography, J. Membr. Sci. 41(1989) 55-67.
[7] S.R. Wickramasinghe, S.E. Bower, Z. Chen, A. Mukherjee, S.M. Husson, Relating the pore size distribution of ultrafiltration membranes to dextran rejection, J. Membr. Sci. 340(2009) 1-8.
[8] R. Rohani, M. Hyland, D. Patterson, A refined one-filtration method for aqueous based nanofiltration and ultrafiltration membrane molecular weight cut-off determination using polyethylene glycols, J. Membr. Sci. 382(2011) 278-290.
[9] H. Susanto, S. Franzka, M. Ulbricht, Dextran fouling of polyethersulfone ultrafiltration membranes-causes, extent and consequences, J. Membr. Sci. 296(2007) 147-155.
[10] M.C.V. Vela, S.Á. Blanco, J.L. García, E.B. Rodríguez, Analysis of membrane pore blocking models applied to the ultrafiltration of PEG, Sep. Purif. Technol. 62(2008) 489-498.
[11] S. Platt, M. Nyström, Amido black staining of ultrafiltration membranes fouled with BSA, Desalination 214(2007) 177-192.
[12] K.C. Khulbe, T. Matsuura, S. Singh, G. Lamarche, S.H. Noh, Study on fouling of ultrafiltration membrane by electron spin resonance, J. Membr. Sci. 167(2000) 263-273.
[13] C. Zhao, X. Zhou, Y. Yue, Determination of pore size and pore size distribution on the surface of hollow fiber filtration membranes:A review of methods, Desalination 129(2000) 107-123.
[14] H. Kamusewitz, M. Schossig-Tiedemann, M. Keller, D. Paul, Characterization of polymeric membranes by means of scanning force microscopy (SFM) in comparison to results of scanning electron microscopy (SEM), Surf. Sci. 377-379(1997) 1076-1081.
[15] A.L. Zydney, A. Xenopoulos, Improving dextran tests for ultrafiltration membranes:effects of device format, J. Membr. Sci. 291(2007) 180-190.
[16] K.J. Hwang, P.Y. Sz, Effect of membrane pore size on the performance of cross-flow microfiltration of BSA/dextran mixtures, J. Membr. Sci. 378(2011) 272-279.
[17] J.K. Leypoldt, Determining pore size distributions of ultrafiltration membranes by solute sieving-mathematical limitations, J. Membr. Sci. 31(1987) 289-305.
[18] H.X. Sun, Q.F. Zheng, Haemolytic activities and adjuvant effect of Gynostemma pentaphyllum saponins on the immune responses to ovalbumin in mice, Phytother. Res. 19(2005) 895-900.
[19] Y.Q. Zhu, Z. Wang, C.X. Zhang, J.X. Wang, S.C. Wang, A novel membrane prepared from sodium alginate cross-linked with sodium tartrate for CO₂ capture, Chin. J. Chem. Eng. 21(10) (2015) 1098-1150.

A convenient method for the determination of molecular weight cut-off of ultrafiltration membranes

A convenient method for the determination of molecular weight cut-off of ultrafiltration membranes

PDF (PC)

Knowledge

Abstract

Cite this article

share this article

References

Related Articles 8

Recommended Articles

Metrics

Comments

[1]	Suhang Jiang, Lijuan Tan, Yujia Tong, Lijian Shi, Weixing Li. A heterogeneous double chamber electro-Fenton with high production of H₂O₂ using La–CeO₂ modified graphite felt as cathode [J]. Chinese Journal of Chemical Engineering, 2023, 54(2): 98-105.
[2]	Eid H. Alosaimi, Ibrahim Hotan Alsohaimi, Hassan M.A. Hassan, Qiao Chen, Saad Melhi, Ayman Abdelaziz Younes. Towards superior permeability and antifouling performance of sulfonated polyethersulfone ultrafiltration membranes modified with sulfopropyl methacrylate functionalized SBA-15 [J]. Chinese Journal of Chemical Engineering, 2023, 53(1): 89-100.
[3]	Sihan Huang, Yaohan Chen, Xue Wang, Jing Guo, Yonggang Li, Lei Dai, Shenghai Li, Suobo Zhang. Preparation of antifouling ultrafiltration membranes from copolymers of polysulfone and zwitterionic poly(arylene ether sulfone)s [J]. Chinese Journal of Chemical Engineering, 2022, 49(9): 100-110.
[4]	Zhenghui Liu, Jun Xiang, Xiaoli Hu, Penggao Cheng, Lei Zhang, Wei Du, Songbo Wang, Na Tang. Effects of coagulation-bath conditions on polyphenylsulfone ultrafiltration membranes [J]. Chinese Journal of Chemical Engineering, 2021, 34(6): 332-340.
[5]	Dongwei Ma, Zhaogen Wang, Tao Liu, Yunxia Hu, Yong Wang. Spray coating of polysulfone/poly(ethylene glycol) block polymer on macroporous substrates followed by selective swelling for composite ultrafiltration membranes [J]. Chinese Journal of Chemical Engineering, 2021, 29(1): 85-91.
[6]	Hao Yang, Jiemei Zhou, Zhaogen Wang, Xiansong Shi, Yong Wang. Selective swelling of polysulfone/poly(ethylene glycol) block copolymer towards fouling-resistant ultrafiltration membranes [J]. Chinese Journal of Chemical Engineering, 2020, 28(1): 98-103.
[7]	Noel Jacob Kaleekkal, A. Thanigaivelan, M. Tarun, D. Mohan. A functional PES membrane for hemodialysis—Preparation, characterization and biocompatibility [J]. Chin.J.Chem.Eng., 2015, 23(7): 1236-1244.
[8]	LUO Mingliang, WEN Qingzhi, LIU Jialin, LIU Hongjian, JIA Zilong. Fabrication of SPES/Nano-TiO₂ Composite Ultrafiltration Membrane and Its Anti-fouling Mechanism [J]. , 2011, 19(1): 45-51.