SCI和EI收录∣中国化工学会会刊

›› 2017, Vol. 25 ›› Issue (1): 62-67.DOI: 10.1016/j.cjche.2016.06.014

• Separation Science and Engineering • Previous Articles     Next Articles

A convenient method for the determination of molecular weight cut-off of ultrafiltration membranes

Cunyu Li1,2, Yun Ma1, Hongyang Li1, Guoping Peng1,2   

  1. 1 Pharmacy College, Nanjing University of Chinese Medicine, Nanjing 210023, China;
    2 Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, Nanjing 210023, China
  • Received:2016-04-15 Revised:2016-06-29 Online:2017-02-15 Published:2017-01-28
  • Supported by:
    Supported by the National Natural Science Foundation of China (No. 81503258, No. 81373980), Youth Natural Science Foundation of Jiangsu Province (No. BK20151005), Science and Technology Project of Jiangsu Traditional Chinese Medicine Administration (No. YB2015009).

A convenient method for the determination of molecular weight cut-off of ultrafiltration membranes

Cunyu Li1,2, Yun Ma1, Hongyang Li1, Guoping Peng1,2   

  1. 1 Pharmacy College, Nanjing University of Chinese Medicine, Nanjing 210023, China;
    2 Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, Nanjing 210023, China
  • 通讯作者: Guoping Peng,E-mail address:guopingpeng@126.com
  • 基金资助:
    Supported by the National Natural Science Foundation of China (No. 81503258, No. 81373980), Youth Natural Science Foundation of Jiangsu Province (No. BK20151005), Science and Technology Project of Jiangsu Traditional Chinese Medicine Administration (No. YB2015009).

Abstract: With the rapid increase of water contamination, membrane separation technology and their corresponding molecular weight cut-off (MWCO) evaluation method become more necessary. In this study, Panax notoginseng saponins was used as a new standard marker to determinate ultrafiltration (UF) membrane MWCOs, series of Millipore membranes were selected as control group to analyze and calculate the relationship between retention rate and MWCOs with exponential or logarithmic equation. A new and convenient method was provided for determining the membrane MWCO by modeling analysis retention rate with MWCOs, and the regression coefficients ≥0.990. The feasibility and practicability of established method was verified by different manufactures' membrane and dextrans. In the detection progress, as the main ingredient of Panax notoginseng saponins, Notoginsenoside R1, Ginsenoside Rg1, Ginsenoside Rb1 and Ginsenoside Rd with different surface activity, the MWCO range of UF membranes can be divided into two zones mainly due to the retention rate difference among Notoginsenoside R1, Ginsenoside Rg1, Ginsenoside Rb1 and Ginsenoside Rd. Zone I, 1000-10000; and Zone II, 10000-100000. Thus, the new method would be helpful to improve the applicability of UF membrane in separation technology.

Key words: Ultrafiltration membrane, Molecular weight cut-off

摘要: With the rapid increase of water contamination, membrane separation technology and their corresponding molecular weight cut-off (MWCO) evaluation method become more necessary. In this study, Panax notoginseng saponins was used as a new standard marker to determinate ultrafiltration (UF) membrane MWCOs, series of Millipore membranes were selected as control group to analyze and calculate the relationship between retention rate and MWCOs with exponential or logarithmic equation. A new and convenient method was provided for determining the membrane MWCO by modeling analysis retention rate with MWCOs, and the regression coefficients ≥0.990. The feasibility and practicability of established method was verified by different manufactures' membrane and dextrans. In the detection progress, as the main ingredient of Panax notoginseng saponins, Notoginsenoside R1, Ginsenoside Rg1, Ginsenoside Rb1 and Ginsenoside Rd with different surface activity, the MWCO range of UF membranes can be divided into two zones mainly due to the retention rate difference among Notoginsenoside R1, Ginsenoside Rg1, Ginsenoside Rb1 and Ginsenoside Rd. Zone I, 1000-10000; and Zone II, 10000-100000. Thus, the new method would be helpful to improve the applicability of UF membrane in separation technology.

关键词: Ultrafiltration membrane, Molecular weight cut-off