Solubility and solution thermodynamics of ammonium dihydrogen phosphate in the water-methanol system

doi:10.1016/j.cjche.2019.02.010

Abstract

Abstract: The solubility of ammonium dihydrogen phosphate (MAP) in the water-methanol system is essential for antisolvent crystallization studies. To investigate the effect of methanol on the solubility of MAP in water, the solubility of MAP in the water-methanol system was determined by dynamic method and static equilibrium method at temperatures ranging from 293.2 to 343.2 K at atmospheric pressure. Results showed that the solubility of MAP increased with the increase of temperature and the increase of water mole fraction in the water-methanol system. The experimental solubility data were correlated with the modified Apelblat equation, the combined nearly ideal binary solvent/Redlich-Kister (CNIBS/R-K) model and the Jouyban-Acree model. The calculated results based on these three models were in very good agreement with the experimental data with the average relative deviations of 0.65%, 0.97%, and 5.38%, respectively. Simultaneously, the thermodynamic properties of the MAP dissolution process in the water-methanol system, including Gibbs energy change, enthalpy, and entropy were obtained by the Van't Hoff equation, which can be used to assess the crystallization process.

Key words: Ammonium dihydrogen phosphate, Solubility, Water-methanol system

摘要： The solubility of ammonium dihydrogen phosphate (MAP) in the water-methanol system is essential for antisolvent crystallization studies. To investigate the effect of methanol on the solubility of MAP in water, the solubility of MAP in the water-methanol system was determined by dynamic method and static equilibrium method at temperatures ranging from 293.2 to 343.2 K at atmospheric pressure. Results showed that the solubility of MAP increased with the increase of temperature and the increase of water mole fraction in the water-methanol system. The experimental solubility data were correlated with the modified Apelblat equation, the combined nearly ideal binary solvent/Redlich-Kister (CNIBS/R-K) model and the Jouyban-Acree model. The calculated results based on these three models were in very good agreement with the experimental data with the average relative deviations of 0.65%, 0.97%, and 5.38%, respectively. Simultaneously, the thermodynamic properties of the MAP dissolution process in the water-methanol system, including Gibbs energy change, enthalpy, and entropy were obtained by the Van't Hoff equation, which can be used to assess the crystallization process.

关键词: Ammonium dihydrogen phosphate, Solubility, Water-methanol system

Dejun Xu, Dehua Xu, Yanjun Zhong, Tao Luo, Xiushan Yang, Zhiye Zhang, Lin Yang, Xinlong Wang. Solubility and solution thermodynamics of ammonium dihydrogen phosphate in the water-methanol system[J]. Chinese Journal of Chemical Engineering, 2019, 27(10): 2518-2525.

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