Measurement and Correlation for Solubility of 2-Chloro-5-chloromethylpyridine in Different Solvents

Abstract

Abstract: 2-Chloro-5-chloromethylpyridine is a crucial intermediate of pesticides.Its solid-liquid equilibrium data will provide essential support for industrial design and further theoretical studies.The solubilities of 2-chloro-5-chloromethylpyridine in water,methanol,ethanol,ethyl acetate,acetone,trichloromethane and toluene at different temperatures were measured using the synthetic method by a laser monitoring observation technique. The solubility data were correlated with the modified Apelblat equation and Wilson equation.The calculated values were in good agreement with the experimental values.

Key words: 2-chloro-5-chloromethylpyridine, solid-liquid equilibrium, solubility

摘要： 2-Chloro-5-chloromethylpyridine is a crucial intermediate of pesticides.Its solid-liquid equilibrium data will provide essential support for industrial design and further theoretical studies.The solubilities of 2-chloro-5-chloromethylpyridine in water,methanol,ethanol,ethyl acetate,acetone,trichloromethane and toluene at different temperatures were measured using the synthetic method by a laser monitoring observation technique. The solubility data were correlated with the modified Apelblat equation and Wilson equation.The calculated values were in good agreement with the experimental values.

关键词: 2-chloro-5-chloromethylpyridine, solid-liquid equilibrium, solubility

SHI Xiaohua, LI Ming, ZHOU Cairong. Measurement and Correlation for Solubility of 2-Chloro-5-chloromethylpyridine in Different Solvents[J]. , 2010, 18(4): 654-658.

石晓华, 李明, 周彩荣. Measurement and Correlation for Solubility of 2-Chloro-5-chloromethylpyridine in Different Solvents[J]. , 2010, 18(4): 654-658.

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