SCI和EI收录∣中国化工学会会刊

›› 2016, Vol. 24 ›› Issue (12): 1680-1686.DOI: 10.1016/j.cjche.2016.04.020

• Separation Science and Engineering • Previous Articles     Next Articles

Adsorption equilibrium for Z-ligustilide on C18-bonded silica from supercritical carbon dioxide

Huisheng Lü, Shuangyan Liu, Yonghui Li, Fanmei Meng, Dawei Yao, Xufei Mo   

  1. Key Laboratory for Green Chemical Technology of Ministry of Education, Tianjin University R & D Center for Petrochemical Technology, Tianjin 300072, China
  • Received:2016-03-01 Revised:2016-04-16 Online:2017-01-04 Published:2016-12-28

Adsorption equilibrium for Z-ligustilide on C18-bonded silica from supercritical carbon dioxide

Huisheng Lü, Shuangyan Liu, Yonghui Li, Fanmei Meng, Dawei Yao, Xufei Mo   

  1. Key Laboratory for Green Chemical Technology of Ministry of Education, Tianjin University R & D Center for Petrochemical Technology, Tianjin 300072, China
  • 通讯作者: Yonghui Li,E-mail address:liyh@tju.edu.cn

Abstract: Adsorption equilibrium is of great importance for the preparative supercritical fluid chromatography (pre-SFC) in defining supercritical adsorption behavior and the industrial amplification. This paper presents adsorption isotherms of Z-ligustilide from supercritical carbon dioxide (SC-CO2) on C18-bonded silica. Adsorption behavior was studied at 305.15 K, 313.15 K and 323.15 K with SC-CO2 density varying from 0.687 g·cm-3 to 0.863 g·cm-3 with the elution by characteristic points (ECP) method. The adsorption amount of Z-ligustilide from SC-CO2 on C18-bonded silica decreased with the increasing density of the mobile phase as well as the increasing temperature. Adsorption equilibrium data were fitted by Langmuir and Freundlich isotherm models, and the Langmuir isotherm model performed better for describing the whole adsorption process on the column. The monolayer saturation adsorption capacity of Z-ligustilide is in the range of 3.0×10-4 mg·cm-3 to 5.5×10-4 mg·cm-3 with an average value of 4.0×10-4 mg·cm-3.

Key words: Z-ligustilide, C18-bonded silica, Pre-SFC, Adsorption equilibrium, Isotherm model

摘要: Adsorption equilibrium is of great importance for the preparative supercritical fluid chromatography (pre-SFC) in defining supercritical adsorption behavior and the industrial amplification. This paper presents adsorption isotherms of Z-ligustilide from supercritical carbon dioxide (SC-CO2) on C18-bonded silica. Adsorption behavior was studied at 305.15 K, 313.15 K and 323.15 K with SC-CO2 density varying from 0.687 g·cm-3 to 0.863 g·cm-3 with the elution by characteristic points (ECP) method. The adsorption amount of Z-ligustilide from SC-CO2 on C18-bonded silica decreased with the increasing density of the mobile phase as well as the increasing temperature. Adsorption equilibrium data were fitted by Langmuir and Freundlich isotherm models, and the Langmuir isotherm model performed better for describing the whole adsorption process on the column. The monolayer saturation adsorption capacity of Z-ligustilide is in the range of 3.0×10-4 mg·cm-3 to 5.5×10-4 mg·cm-3 with an average value of 4.0×10-4 mg·cm-3.

关键词: Z-ligustilide, C18-bonded silica, Pre-SFC, Adsorption equilibrium, Isotherm model