Preparation and modification of membranes for extracorporeal membrane oxygenator: A review

doi:10.1016/j.cjche.2024.04.031

Abstract

Abstract: Extracorporeal membrane oxygenation (ECMO) has been developed for nearly 70 years, and it is the main technology to treat cardiopulmonary failure and continue to maintain life. As the core component of the ECMO system, the gas exchange membrane possesses low gas permeability and plasma leakage at present. In addition, the membrane material exists low blood compatibility, causing the formation of thrombosis. Therefore, the membrane material with high gas permeability and blood compatibility are urgently needed. This paper summarizes the membrane development process, preparation method, and modification method. It provides a new idea for the preparation and coating modification as artificial lung membrane.

摘要： Extracorporeal membrane oxygenation (ECMO) has been developed for nearly 70 years, and it is the main technology to treat cardiopulmonary failure and continue to maintain life. As the core component of the ECMO system, the gas exchange membrane possesses low gas permeability and plasma leakage at present. In addition, the membrane material exists low blood compatibility, causing the formation of thrombosis. Therefore, the membrane material with high gas permeability and blood compatibility are urgently needed. This paper summarizes the membrane development process, preparation method, and modification method. It provides a new idea for the preparation and coating modification as artificial lung membrane.

Donghai Sheng, Lin Zhang, Guo Yang, Baoming Guo, Longsheng Lin, Yongqi Shi, Song Yuan, Jinnan Wang, Yuan Li, Beibei Feng. Preparation and modification of membranes for extracorporeal membrane oxygenator: A review[J]. Chinese Journal of Chemical Engineering, 2025, 82(6): 39-56.

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