Adsorption equilibrium of citric acid from supercritical carbon dioxide/ethanol on cyano column

doi:10.1016/j.cjche.2013.10.002

Abstract

Abstract: Supercritical adsorption equilibrium has a significant role in defining supercritical adsorption behavior. In this paper, the adsorption equilibrium of citric acid from supercritical CO₂/ethanol on a cyano column was systematically investigatedwith the elution by characteristic pointmethod. Equilibriumloadingwas obtained at 313.15 K and 321.15 K with supercritical CO₂/ethanol densities varying from0.7068 g·cm^-3 to 0.8019 g·cm^-3. The experimental results showed that the adsorption capacity of citric acid decreasedwith increasing temperature and increasing density of the supercritical CO₂/ethanol mobile phase. The adsorption equilibrium data were fitted well by the Quadratic Hill isotherm model and the isotherms showed anti-Langmuir behavior. Themonolayer saturation adsorption capacity of citric acid is in the range of 44.54mg·cm^-3 to 64.66mg·cm^-3 with an average value of 56.86 mg·cm^-3.

Key words: Adsorption isotherm, Citric acid, Cyano column, Isotherm model

摘要： Supercritical adsorption equilibrium has a significant role in defining supercritical adsorption behavior. In this paper, the adsorption equilibrium of citric acid from supercritical CO₂/ethanol on a cyano column was systematically investigatedwith the elution by characteristic pointmethod. Equilibriumloadingwas obtained at 313.15 K and 321.15 K with supercritical CO₂/ethanol densities varying from0.7068 g·cm^-3 to 0.8019 g·cm^-3. The experimental results showed that the adsorption capacity of citric acid decreasedwith increasing temperature and increasing density of the supercritical CO₂/ethanol mobile phase. The adsorption equilibrium data were fitted well by the Quadratic Hill isotherm model and the isotherms showed anti-Langmuir behavior. Themonolayer saturation adsorption capacity of citric acid is in the range of 44.54mg·cm^-3 to 64.66mg·cm^-3 with an average value of 56.86 mg·cm^-3.

关键词: Adsorption isotherm, Citric acid, Cyano column, Isotherm model

Huisheng Lü, GuoqingWang, Minhua Zhang, Zhongfeng Geng, Miao Yang, Yanpeng Sun. Adsorption equilibrium of citric acid from supercritical carbon dioxide/ethanol on cyano column[J]. Chin.J.Chem.Eng., 2015, 23(6): 905-911.

References

[1] A. Karthikeyan, N. Sivakumar, Citric acid production by Koji fermentation using banana peel as novel substrate, Bioresour. Technol. 101 (2010) 5552-5556.

[2] J.L.Wu, Q.J. Peng,W. Arlt,M. Minceva, Model-based design of a pilot-scale simulated moving bed for purification of citric acid from fermentation broth, J. Chromatogr. A 50 (2009) 8793-8805.

[3] Y.S.Mostafa, S.A. Alamri, Optimization of date syrup for enhancement of the production of citric acid using immobilized cells of Aspergillus niger, Saudi J. Biol. Sci. 19 (2012) 241-246.

[4] G. Guiochon, A. Tarafder, Fundamental challenges and opportunities for preparative supercritical fluid chromatography, J. Chromatogr. A 1218 (2011) 1037-1114.

[5] W.P. Farrell, C.M. Aurigemma, D.F.Masters-Moore, Advances in high throughput supercritical fluid chromatography, J. Liq. Chromatogr. Relat. Technol. 32 (2009) 1689-1710.

[6] M.A. Patel, F. Riley, J.Wang, M. Lovdahl, L.T. Taylor, Packed column supercritical fluid chromatography of isomeric polypeptide pairs, J. Chromatogr. A 1218 (2011) 2593-2597.

[7] C. Desmortreux, M. Rothaupt, C. West, E. Lesellier, Improved separation of furocoumarins of essential oils by supercritical fluid chromatography, J. Chromatogr. A 1216 (2009) 7088-7095.

[8] S. Chilamkurthi, J.H. Willemsen, A.M. Luuk, L.A.M. van der Wielen, E. Poiesz, M. Ottens, High-throughput determination of adsorption equilibria for chromatographic oligosaccharide separations, J. Chromatogr. A 1239 (2012) 22-34.

[9] N. Marchetti, A. Cavazzini, L. Pasti, F. Dondi, Determination of adsorption isotherms by means of HPLC: adsorption mechanism elucidation and separation optimization, J. Sep. Sci. 32 (2009) 727-741.

[10] M.H. Chuang, M. Johannsen, Solubilities and adsorption equilibria of β-carotene in supercritical and near-critical fluids, Chem. Eng. Data 56 (2011) 1770-1777.

[11] C. Domingo, J. Garcia-Carmona, M.A. Fanovich, J. Llibre, R. Rodriguez-Clemente, Single or two-solute adsorption processes at supercritical conditions: An experimental study, J. Supercrit. Fluids 21 (2001) 147-157.

[12] I. Kikic, P. Alessi, A. Cortesi, S.J.Macnaughton, N.R. Foster, B. Spicka, An experimental study of supercritical adsorption equilibria salicylic acid on activated carbon, Fluid Phase Equilib. 117 (1996) 304-311.

[13] R. Harikrishnan, M.P. Srinivasan, C.B. Ching, Adsorption of ethyl benzene on activated carbon from supercritical CO₂, AICHE J. 44 (1998) 2620-2627.

[14] C.S. Tan, D.C. Liou, Adsorption equilibriumof toluene fromsupercritical carbon dioxide on activated carbon, Ind. Eng. Chem. Res. 29 (1990) 1412-1415.

[15] C.S. Tan, D.C. Liou, Desorption of ethyl acetate fromactivated carbon by supercritical carbon dioxide, Ind. Eng. Chem. Res. 27 (1988) 988-991.

[16] D. Bolten, M. Johannsen, Influence of 2-propanol on adsorption equilibria of α- tocopherol and δ-tocopherol from supercritical carbon dioxide on silica gel, J. Chem. Eng. Data 51 (2006) 2132-2137.

[17] M. Lubbert, G. Brunner, M. Johannsen, Adsorption equilibria of α-tocopherol and δ- tocopherol from supercritical mixtures of carbon dioxide and 2-propanol onto silica by means of perturbation chromatography, J. Supercrit. Fluids 42 (2007) 180-188.

[18] E. Reverchon, G. Lamberti, P. Subra,Modeling and simulation of the supercritical adsorption of complex terpene mixtures, Chem. Eng. Sci. 53 (1998) 3537-3544.

[19] P. Subra, A. Vega-Bancel, E. Reverchon, Breakthrough curves and adsorption isotherms of terpene mixtures in supercritical carbon dioxide, J. Supercrit. Fluids 12 (1998) 43-57.

[20] S. Lucas, M.J. Cocero, C. Zetzl, G. Brunner, Adsorption isotherms for ethylacetate and furfural on activated carbon from supercritical carbon dioxide, Fluid Phase Equilib. 219 (2004) 171-179.

[21] J. Gregorowicz, Adsorption of eicosane and 1,2-hexanediol fromsupercritical carbon dioxide on activated carbon and chromosorb, Fluid Phase Equilib. 238 (2005) 142-148.

[22] L. Ravald, T. Fornstedt, Theoretical study of the accuracy of the elution by characteristic points method for bi-Langmuir isotherms, J. Chromatogr. A 908 (2001) 111-130.

[23] T. Zhu, M.L. Tian, K.H. Row, Comparison of adsorption equilibrium of glycyrrhizic acid and liquiritin on C₁₈ column, J. Ind. Eng. Chem. 16 (2010) 929-934.

[24] G. Brunner, M. Johannsen, New aspects on adsorption from supercritical fluid phases, J. Supercrit. Fluids 38 (2006) 181-200.

[25] C. West, E. Lesellier, A unified classification of stationary phases for packed column supercritical fluid chromatography, J. Chromatogr. A 1191 (2008) 21-39.

[26] D. Rigby, Fluid density predictions using the COMPASS force field, Fluid Phase Equilib. 217 (2004) 77-87.

[27] K. Miyabe, S. Khattabi, D.E. Cherrak, G. Guiochon, Study on the accuracy of the elution by characteristic point method for the determination of single component isotherms, J. Chromatogr. A 872 (2000) 1-21.

[28] H. Guan, B.J. Stanley, G. Guiochon, Theoretical study of the accuracy and precision of the measurement of single-component isotherms by the elution by characteristic point method, J. Chromatogr. 659 (1994) 27-41.

[29] J.R. Strubinger, H.C. Song, J.F. Parcher, High-pressure phase distribution isotherms for supercritical fluid chromatographic systems. 1. Pure carbon dioxide, Anal. Chem. 63 (1991) 98-103.

[30] J.R. Strubinger, H.C. Song, J.F. Parcher, High-pressure phase distribution isotherms for supercritical fluid chromatographic systems. 2. Binary isotherms of carbon dioxide and methanol, Anal. Chem. 63 (1991) 104-108.

[31] G. Guiochon, A. Felinger, D.G. Shirazi, A.M. Katti, Fundamentals of Preparative and Nonlinear Chromatography, Academic Press, Boston, 1994.