SCI和EI收录∣中国化工学会会刊

›› 2008, Vol. 16 ›› Issue (4): 503-516.

• REVIEWS • Previous Articles     Next Articles

A State-of-the-Art Review of Mixing in Microfluidic Mixers

Elmabruk A. Mansur, YE Mingxing, WANG Yundong, DAI Youyuan   

  1. The State Key Laboratory of Chemical Engineering, Department of Chemical Engineering, Tsinghua University, Beijing 100084, China
  • Received:2007-07-12 Revised:2008-04-14 Online:2008-08-28 Published:2008-08-28
  • Supported by:
    the National High Technology Research and Development Program of China(2006AA030202,2006AA05Z316)

A State-of-the-Art Review of Mixing in Microfluidic Mixers

Elmabruk A. Mansur, 叶明星, 王运东, 戴猷元   

  1. The State Key Laboratory of Chemical Engineering, Department of Chemical Engineering, Tsinghua University, Beijing 100084, China
  • 通讯作者: WANG Yundong, E-mail: wangyd@tsinghua.edu.cn
  • 基金资助:
    the National High Technology Research and Development Program of China(2006AA030202,2006AA05Z316)

Abstract: Microreaction technology is one of the most innovative and rapid developing fields in chemical engineering, synthesis and process technology. Many expectations toward enhanced product selectivity, yield and purity, improved safety, and access to new products and processes are directed to the microreaction technology. Microfluidic mixer is the most important component in microfluidic devices. Based on various principles, active and passive micromixers have been designed and investigated. This review is focused on the recent developments in microfluidic mixers. An overview of the flow phenomena and mixing characteristics in active and passive micromixers is presented, including the types of physical phenomena and their utilization in micromixers. Due to the simple fabrication technology and the easy implementation in a complex microfluidic system, T-micromixer is highlighted as an example to illustrate the effect of design and operating parameters on mixing efficiency and fluid flow inside microfluidic mixers.

Key words: micromixing, microfluidics, T-shaped micromixer, microfabrication techniques, microreaction technologies, microelectromechanical systems

摘要: Microreaction technology is one of the most innovative and rapid developing fields in chemical engineering, synthesis and process technology. Many expectations toward enhanced product selectivity, yield and purity, improved safety, and access to new products and processes are directed to the microreaction technology. Microfluidic mixer is the most important component in microfluidic devices. Based on various principles, active and passive micromixers have been designed and investigated. This review is focused on the recent developments in microfluidic mixers. An overview of the flow phenomena and mixing characteristics in active and passive micromixers is presented, including the types of physical phenomena and their utilization in micromixers. Due to the simple fabrication technology and the easy implementation in a complex microfluidic system, T-micromixer is highlighted as an example to illustrate the effect of design and operating parameters on mixing efficiency and fluid flow inside microfluidic mixers.

关键词: micromixing, microfluidics, T-shaped micromixer, microfabrication techniques, microreaction technologies, microelectromechanical systems