The biomimetic catalytic synthesis of acetal compounds using β-cyclodextrin as catalyst

doi:10.1016/j.cjche.2015.06.008

Abstract

Abstract: Based on the principle of biomimetic catalysis, β-cyclodextrin was applied to the acetalation reaction as a facile and efficient catalyst, and the synthesis was environmentally friendly with atomic economy. The influencing factors of the acetalation reaction e.g. the reaction time, the volume of water-carrying agent, the molar ratio of catalyst to benzaldehyde and the molar ratio of glycol to benzaldehyde had been studied. The yield of benzaldehyde glycol acetal would reach amaximum of 81.3% under the conditions approached. Six of other acetals were also synthesized. Moreover, a plausible reaction mechanism for the formation of acetal had been proposed.

Key words: &, beta, -Cyclodextrin, Biomimetic catalysis, Synthesis, Acetal

摘要： Based on the principle of biomimetic catalysis, β-cyclodextrin was applied to the acetalation reaction as a facile and efficient catalyst, and the synthesis was environmentally friendly with atomic economy. The influencing factors of the acetalation reaction e.g. the reaction time, the volume of water-carrying agent, the molar ratio of catalyst to benzaldehyde and the molar ratio of glycol to benzaldehyde had been studied. The yield of benzaldehyde glycol acetal would reach amaximum of 81.3% under the conditions approached. Six of other acetals were also synthesized. Moreover, a plausible reaction mechanism for the formation of acetal had been proposed.

关键词: &, beta, -Cyclodextrin, Biomimetic catalysis, Synthesis, Acetal

Daohong Xia, Shengjuan Jiang, Lantao Li, Yuzhi Xiang, Lijun Zhu. The biomimetic catalytic synthesis of acetal compounds using β-cyclodextrin as catalyst[J]. Chin.J.Chem.Eng., 2016, 24(1): 146-150.

Daohong Xia, Shengjuan Jiang, Lantao Li, Yuzhi Xiang, Lijun Zhu. The biomimetic catalytic synthesis of acetal compounds using β-cyclodextrin as catalyst[J]. Chinese Journal of Chemical Engineering, 2016, 24(1): 146-150.

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