The effect of operating conditions on acylation of 2-methylnaphthalene in a microchannel reactor

doi:10.1016/j.cjche.2018.01.004

Chin.J.Chem.Eng. ›› 2018, Vol. 26 ›› Issue (6): 1307-1311.DOI: 10.1016/j.cjche.2018.01.004

• Catalytic reactor & ISMR • Previous Articles Next Articles

The effect of operating conditions on acylation of 2-methylnaphthalene in a microchannel reactor

Wenpeng Li, Suohe Yang, Xiaoyan Guo, Guangxiang He, Haibo Jin

Beijing Key Laboratory of Fuels Cleaning and Advanced Catalytic Emission Reduction Technology, College of Chemical Engineering, Beijing Institute of Petrochemical Technology, Beijing 101617, China

Received:2017-10-25 Revised:2018-01-10 Online:2018-08-03 Published:2018-06-28
Contact: Haibo Jin,E-mail address:jinhaibo@bipt.edu.cn
Supported by:
Supported by the National Natural Science Foundation of China (91634101) and The Project of Construction of Innovative Teams and Teacher Career Development for Universities and Colleges under Beijing Municipality (IDHT20180508).

The effect of operating conditions on acylation of 2-methylnaphthalene in a microchannel reactor

Wenpeng Li, Suohe Yang, Xiaoyan Guo, Guangxiang He, Haibo Jin

Beijing Key Laboratory of Fuels Cleaning and Advanced Catalytic Emission Reduction Technology, College of Chemical Engineering, Beijing Institute of Petrochemical Technology, Beijing 101617, China

通讯作者: Haibo Jin,E-mail address:jinhaibo@bipt.edu.cn
基金资助:
Supported by the National Natural Science Foundation of China (91634101) and The Project of Construction of Innovative Teams and Teacher Career Development for Universities and Colleges under Beijing Municipality (IDHT20180508).

Abstract

Abstract: Acylation of 2-methylnaphthalene (2-MN) is a very important reaction in organic synthesis, and the effiency of the continuous reactor is more than one of the batch reactor. Considering that the Friedel-Crafts acylation is a rapid exothermic reaction, in this study, we perform the acylation of 2-MN in a stainless steel microchannel flow reactor, which is characterized by high mass and heat transfer rates. The effect of reactant ratio, mixing temperature, reaction temperature, and reaction time on product yield and selectivity were investigated. Under the optimal conditions, 2-methyl-6-propionylnaphthalene (2,6-MPN) was obtained in 85.8% yield with 87.5% selectivity. Compared with the conventional batch system, the continuous flow microchannel reactor provides a more efficient method for the synthesis of 2,6-MPN.

Key words: Acylation, Microchannel reactor, 2-Methylnaphthalene, 2-Methyl-6-propionylnaphthalene

摘要： Acylation of 2-methylnaphthalene (2-MN) is a very important reaction in organic synthesis, and the effiency of the continuous reactor is more than one of the batch reactor. Considering that the Friedel-Crafts acylation is a rapid exothermic reaction, in this study, we perform the acylation of 2-MN in a stainless steel microchannel flow reactor, which is characterized by high mass and heat transfer rates. The effect of reactant ratio, mixing temperature, reaction temperature, and reaction time on product yield and selectivity were investigated. Under the optimal conditions, 2-methyl-6-propionylnaphthalene (2,6-MPN) was obtained in 85.8% yield with 87.5% selectivity. Compared with the conventional batch system, the continuous flow microchannel reactor provides a more efficient method for the synthesis of 2,6-MPN.

关键词: Acylation, Microchannel reactor, 2-Methylnaphthalene, 2-Methyl-6-propionylnaphthalene

Wenpeng Li, Suohe Yang, Xiaoyan Guo, Guangxiang He, Haibo Jin. The effect of operating conditions on acylation of 2-methylnaphthalene in a microchannel reactor[J]. Chin.J.Chem.Eng., 2018, 26(6): 1307-1311.

Wenpeng Li, Suohe Yang, Xiaoyan Guo, Guangxiang He, Haibo Jin. The effect of operating conditions on acylation of 2-methylnaphthalene in a microchannel reactor[J]. Chinese Journal of Chemical Engineering, 2018, 26(6): 1307-1311.

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The effect of operating conditions on acylation of 2-methylnaphthalene in a microchannel reactor

The effect of operating conditions on acylation of 2-methylnaphthalene in a microchannel reactor

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