Pretreatment of Isopropanol Solution from Pharmaceutical Industry and Pervaporation Dehydration by NaA Zeolite Membranes

›› 2011, Vol. 19 ›› Issue (6): 904-910.

• SEPARATION SCIENCE AND ENGINEERING • Previous Articles Next Articles

Pretreatment of Isopropanol Solution from Pharmaceutical Industry and Pervaporation Dehydration by NaA Zeolite Membranes

YU Congli, LIU Yanmei, CHEN Gangling, GU Xuehong, XING Weihong

State Key Laboratory of Materials-Oriented Chemical Engineering, Nanjing University of Technology, Nanjing 210009, China

Received:2010-11-11 Revised:2011-07-31 Online:2012-04-24 Published:2011-12-28
Supported by:
Supported by the National Basic Research Program of China (2009CB623403);the National High Technology Research and Development Program of China (2009AA034802);the National Natural Science Foundation of China (20706030, U0834004);the Science & Technology Support Program (Industry) of Jiangsu Province of China (BE2008141);the Natural Science Foundation of the Jiangsu Higher Education Institutions (09KJA530002);333 High-Level Personnel Training Project in Jiangsu Province

Pretreatment of Isopropanol Solution from Pharmaceutical Industry and Pervaporation Dehydration by NaA Zeolite Membranes

余从立, 刘艳梅, 陈纲领, 顾学红, 邢卫红

State Key Laboratory of Materials-Oriented Chemical Engineering, Nanjing University of Technology, Nanjing 210009, China

通讯作者: GU Xuehong, E-mail: Xuehonggu@yahoo.com
基金资助:
Supported by the National Basic Research Program of China (2009CB623403);the National High Technology Research and Development Program of China (2009AA034802);the National Natural Science Foundation of China (20706030, U0834004);the Science & Technology Support Program (Industry) of Jiangsu Province of China (BE2008141);the Natural Science Foundation of the Jiangsu Higher Education Institutions (09KJA530002);333 High-Level Personnel Training Project in Jiangsu Province

Abstract

Abstract: NaA zeolite membranes with 80 cm in length and 12.8 mm in outer diameter were prepared by our research group cooperating with Nanjing Jiusi Hi-Tech Co., China. The influence of dissolved inorganic salts and pH value in the feed of isopropanol (IPA) solution on NaA zeolite membranes was investigated. It was found that both factors exhibited strong influence on the stability of NaA zeolite membranes. A set of pretreatment steps such as pH adjustment and distillation of the IPA solution were proposed to improve stability for pervaporation dehydration. An industrial-scale pervaporation facility with 52 m² membrane area was built to dehydrate IPA solution from industrial cephalosporin production. The facility was continuously operated at 368-378 K to dehydrate IPA solution from water mass content of 15%-20% to less than 2% with a feed flow rate of 400-500 L·h^-1 and an average water flux of 1-1.5 kg·m^-2·h^-1. The successful application of this facility suggested a promising application of NaA zeolite mem-brane for IPA recovery from pharmaceutical production.

Key words: NaA zeolite membrane, isopropanol, dehydration, pervaporation

摘要： NaA zeolite membranes with 80 cm in length and 12.8 mm in outer diameter were prepared by our research group cooperating with Nanjing Jiusi Hi-Tech Co., China. The influence of dissolved inorganic salts and pH value in the feed of isopropanol (IPA) solution on NaA zeolite membranes was investigated. It was found that both factors exhibited strong influence on the stability of NaA zeolite membranes. A set of pretreatment steps such as pH adjustment and distillation of the IPA solution were proposed to improve stability for pervaporation dehydration. An industrial-scale pervaporation facility with 52 m² membrane area was built to dehydrate IPA solution from industrial cephalosporin production. The facility was continuously operated at 368-378 K to dehydrate IPA solution from water mass content of 15%-20% to less than 2% with a feed flow rate of 400-500 L·h^-1 and an average water flux of 1-1.5 kg·m^-2·h^-1. The successful application of this facility suggested a promising application of NaA zeolite mem-brane for IPA recovery from pharmaceutical production.

关键词: NaA zeolite membrane, isopropanol, dehydration, pervaporation

YU Congli, LIU Yanmei, CHEN Gangling, GU Xuehong, XING Weihong. Pretreatment of Isopropanol Solution from Pharmaceutical Industry and Pervaporation Dehydration by NaA Zeolite Membranes[J]. , 2011, 19(6): 904-910.

余从立, 刘艳梅, 陈纲领, 顾学红, 邢卫红. Pretreatment of Isopropanol Solution from Pharmaceutical Industry and Pervaporation Dehydration by NaA Zeolite Membranes[J]. , 2011, 19(6): 904-910.

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Pretreatment of Isopropanol Solution from Pharmaceutical Industry and Pervaporation Dehydration by NaA Zeolite Membranes

Pretreatment of Isopropanol Solution from Pharmaceutical Industry and Pervaporation Dehydration by NaA Zeolite Membranes

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