SCI和EI收录∣中国化工学会会刊

Chinese Journal of Chemical Engineering ›› 2022, Vol. 49 ›› Issue (9): 21-33.DOI: 10.1016/j.cjche.2022.03.011

• Special Column: Membranes for Life Science • Previous Articles     Next Articles

Short review on liquid membrane technology and their applications in biochemical engineering

Wenjun Zhang1,2, Wenshu Ge1,2, Min Li1, Shuangqing Li1,2, Minqiang Jiang1,2, Xiujuan Zhang1,2, Gaohong He1,2   

  1. 1. State Key Laboratory of Fine Chemicals, Dalian University of Technology, Dalian 116023, China;
    2. School of Chemical Engineering, Dalian University of Technology, Panjin 124221, China
  • Received:2021-09-30 Revised:2022-03-02 Online:2022-10-19
  • Contact: Gaohong He,E-mail:hgaohong@dlut.edu.cn
  • Supported by:
    The authors sincerely acknowledge the support of National Natural Science Foundation of China (21506028), National Key Research and Development Program of China (2019YFE0119200), and Fundamental Research Funds for the Central Universities (DUT20LK43).

Short review on liquid membrane technology and their applications in biochemical engineering

Wenjun Zhang1,2, Wenshu Ge1,2, Min Li1, Shuangqing Li1,2, Minqiang Jiang1,2, Xiujuan Zhang1,2, Gaohong He1,2   

  1. 1. State Key Laboratory of Fine Chemicals, Dalian University of Technology, Dalian 116023, China;
    2. School of Chemical Engineering, Dalian University of Technology, Panjin 124221, China
  • 通讯作者: Gaohong He,E-mail:hgaohong@dlut.edu.cn
  • 基金资助:
    The authors sincerely acknowledge the support of National Natural Science Foundation of China (21506028), National Key Research and Development Program of China (2019YFE0119200), and Fundamental Research Funds for the Central Universities (DUT20LK43).

Abstract: As a branch of membrane separation technology, liquid membrane has attracted great attention and expanded investigations in biological chemical engineering, with life and health concern in ecosystems. Composed of membrane solvent and mobile carrier, liquid membrane was acquired of function, performing the facilitated mass transfer across the diffusive solvent, so as for the separation and delivery achievement with efficacy. In this review, two types of liquid membrane are mainly focused, respectively on supported liquid membrane (SLM) of membrane solvent supporter in necessity, and on emulsion liquid membrane (ELM) of the required interfacial stabilizers and homogenization. Accordingly, the transfer mechanism, compositions, structure and features of SLM and ELM are introduced respectively. Moreover, the current investigations of liquid membrane have been discussed, focusing on the improvements of efficacy and stability in separation & detection, encapsulation and delivery, so as to scale up the favorable and efficient application with bio-life concern. Prospectively, this review could provide comprehensive insight into the bio-applications of liquid membrane, and guidelines for the further investigations on the efficacy and long-term applicable stability, in order to realize the industrialization.

Key words: Liquid membrane, Membrane separation, Membrane encapsulation, Delivery vehicle, Bio-application

摘要: As a branch of membrane separation technology, liquid membrane has attracted great attention and expanded investigations in biological chemical engineering, with life and health concern in ecosystems. Composed of membrane solvent and mobile carrier, liquid membrane was acquired of function, performing the facilitated mass transfer across the diffusive solvent, so as for the separation and delivery achievement with efficacy. In this review, two types of liquid membrane are mainly focused, respectively on supported liquid membrane (SLM) of membrane solvent supporter in necessity, and on emulsion liquid membrane (ELM) of the required interfacial stabilizers and homogenization. Accordingly, the transfer mechanism, compositions, structure and features of SLM and ELM are introduced respectively. Moreover, the current investigations of liquid membrane have been discussed, focusing on the improvements of efficacy and stability in separation & detection, encapsulation and delivery, so as to scale up the favorable and efficient application with bio-life concern. Prospectively, this review could provide comprehensive insight into the bio-applications of liquid membrane, and guidelines for the further investigations on the efficacy and long-term applicable stability, in order to realize the industrialization.

关键词: Liquid membrane, Membrane separation, Membrane encapsulation, Delivery vehicle, Bio-application