Electrocatalytic glucose oxidation activity of Ni/CNT composites based on low-temperature discharge synthesis

doi:10.1016/j.cjche.2025.05.025

Chinese Journal of Chemical Engineering ›› 2025, Vol. 86 ›› Issue (10): 114-122.DOI: 10.1016/j.cjche.2025.05.025

Previous Articles Next Articles

Electrocatalytic glucose oxidation activity of Ni/CNT composites based on low-temperature discharge synthesis

Yulong Men¹, Haoxin Chen², Jianqiao Wang³, Jiafu Zou¹, Yan Chen¹, Ning Dou⁴, Peng Liu¹, Yunxiang Pan¹

1. School of Chemistry and Chemical Engineering, Shanghai Jiao Tong University, Shanghai 200240, China;
2. The College of Nuclear Technology and Automation Engineering, Chengdu University of Technology, Chengdu 610059, China;
3. Fuzhou Trafficinfo Certification &Testing Co. Ltd., Fuzhou 350011, China;
4. Vascular Disease Center, Shanghai Fourth People's Hospital Affiliated to Tongji University School of Medicine, Shanghai 200081, China

Received:2025-03-25 Revised:2025-05-16 Accepted:2025-05-20 Online:2025-07-01 Published:2025-10-28
Contact: Yulong Men,E-mail:menyulong1988@sjtu.edu.cn;Ning Dou,E-mail:woshidouning@163.com;Peng Liu,E-mail:liupeng715@sjtu.edu.cn
Supported by:
This work was supported by the National Natural Science Foundation of China (22408225 and 22478241) and the Postdoctoral Fellowship Program of CPSF (GZC20240999).

Electrocatalytic glucose oxidation activity of Ni/CNT composites based on low-temperature discharge synthesis

Yulong Men¹, Haoxin Chen², Jianqiao Wang³, Jiafu Zou¹, Yan Chen¹, Ning Dou⁴, Peng Liu¹, Yunxiang Pan¹

1. School of Chemistry and Chemical Engineering, Shanghai Jiao Tong University, Shanghai 200240, China;
2. The College of Nuclear Technology and Automation Engineering, Chengdu University of Technology, Chengdu 610059, China;
3. Fuzhou Trafficinfo Certification &Testing Co. Ltd., Fuzhou 350011, China;
4. Vascular Disease Center, Shanghai Fourth People's Hospital Affiliated to Tongji University School of Medicine, Shanghai 200081, China

通讯作者: Yulong Men,E-mail:menyulong1988@sjtu.edu.cn;Ning Dou,E-mail:woshidouning@163.com;Peng Liu,E-mail:liupeng715@sjtu.edu.cn
基金资助:
This work was supported by the National Natural Science Foundation of China (22408225 and 22478241) and the Postdoctoral Fellowship Program of CPSF (GZC20240999).

Abstract

Abstract: Electrochemical reaction is emerging as a powerful approach for glucose detection and biomass conversion. However, it has been rarely explored for glucose detection and biomass conversion into value-added chemicals. Previously reported glucose oxidase reduction (GOR) catalysts exhibit issues such as low activity, limited detection range, poor sensitivity, and overreliance on noble metals. Here, we employ an impregnation method to load transition metal nickel onto carbon nanotubes (CNT) and fabricated Ni/CNT30 catalyst via a discharge process. Ni/CNT30 catalyst exhibits a remarkably high catalytic activity of up to 3336.7 μA·cm^-2·mmol^-1·L, a detection limit of 2.43 μmol·L^-1, outstanding stability, and excellent resistance to impurities and interference, surpassing other noble metal-based and oxide-based materials. Hence, this material provides a new approach for the preparation of glucose sensors to achieve precise mobile measurement of glucose concentration and biofuel cells in future.

Key words: Interface, Electrocatalysis, Nickel-based, Glucose, Oxidation

摘要： Electrochemical reaction is emerging as a powerful approach for glucose detection and biomass conversion. However, it has been rarely explored for glucose detection and biomass conversion into value-added chemicals. Previously reported glucose oxidase reduction (GOR) catalysts exhibit issues such as low activity, limited detection range, poor sensitivity, and overreliance on noble metals. Here, we employ an impregnation method to load transition metal nickel onto carbon nanotubes (CNT) and fabricated Ni/CNT30 catalyst via a discharge process. Ni/CNT30 catalyst exhibits a remarkably high catalytic activity of up to 3336.7 μA·cm^-2·mmol^-1·L, a detection limit of 2.43 μmol·L^-1, outstanding stability, and excellent resistance to impurities and interference, surpassing other noble metal-based and oxide-based materials. Hence, this material provides a new approach for the preparation of glucose sensors to achieve precise mobile measurement of glucose concentration and biofuel cells in future.

关键词: Interface, Electrocatalysis, Nickel-based, Glucose, Oxidation

Yulong Men, Haoxin Chen, Jianqiao Wang, Jiafu Zou, Yan Chen, Ning Dou, Peng Liu, Yunxiang Pan. Electrocatalytic glucose oxidation activity of Ni/CNT composites based on low-temperature discharge synthesis[J]. Chinese Journal of Chemical Engineering, 2025, 86(10): 114-122.

References

[1] R.Y. Pan, L. He, J. Zhang, X.H. Liu, Y.J. Liao, J. Gao, Y. Liao, Y.H. Yan, Q.Q. Li, X.H. Zhou, J.B. Cheng, Q. Xing, F.X. Guan, J. Zhang, L.Y. Sun, Z.Q. Yuan, Positive feedback regulation of microglial glucose metabolism by histone H4 lysine 12 lactylation in Alzheimer’s disease, Cell Metab. 34 (4) (2022) 634-648.e6.
[2] Y. An, V.R. Varma, S. Varma, R. Casanova, E. Dammer, O. Pletnikova, C.W. Chia, J.M. Egan, L. Ferrucci, J. Troncoso, A.I. Levey, J. Lah, N.T. Seyfried, C. Legido-Quigley, R. O’Brien, M. Thambisetty, Evidence for brain glucose dysregulation in Alzheimer’s disease, Alzheimers Dement. 14 (3) (2018) 318-329.
[3] L.H. Zhu, Z.G. She, X. Cheng, J.J. Qin, X.J. Zhang, J.J. Cai, F. Lei, H.T. Wang, J. Xie, W.X. Wang, H.M. Li, P. Zhang, X.H. Song, X. Chen, M. Xiang, C.Z. Zhang, L.J. Bai, D. Xiang, M.M. Chen, Y.Q. Liu, Y.Q. Yan, M.Y. Liu, W.M. Mao, J.J. Zou, L.M. Liu, G.H. Chen, P.C. Luo, B. Xiao, C.J. Zhang, Z.X. Zhang, Z.G. Lu, J.H. Wang, H.F. Lu, X.G. Xia, D.H. Wang, X.F. Liao, G. Peng, P. Ye, J. Yang, Y.F. Yuan, X.D. Huang, J. Guo, B.H. Zhang, H.L. Li, Association of blood glucose control and outcomes in patients with COVID-19 and pre-existing type 2 diabetes, Cell Metab. 31 (6) (2020) 1068-1077.e3.
[4] S.L. Liu, W. Zeng, Q. Guo, Y.Q. Li, Metal oxide-based composite for non-enzymatic glucose sensors, J. Mater. Sci. Mater. Electron. 31 (19) (2020) 16111-16136.
[5] X.K. Wang, L. Hao, R.X. Du, H. Wang, J.X. Dong, Y.F. Zhang, Synthesis of unique three-dimensional CoMn2O4@Ni(OH)2 nanocages via Kirkendall effect for non-enzymatic glucose sensing, J. Colloid Interface Sci. 653 (2024) 730-740.
[6] M.R. Chang, L. Hao, X.Y. Li, H. Wang, N. Fu, Y.F. Zhang, Boosting the performance of enzyme-free biosensing system with Ni-Co bimetallic nanorod anchored on macroporous carbon composites for glucose monitoring, Mater. Res. Bull. 169 (2024) 112541.
[7] Y.B. Chen, L. Hao, D.H. Sun, J.X. Dong, Y.F. Zhang, Novel synthesis of cube-like cupric oxide doping on Co species embedded in hollow nanoporous carbon for non-enzymatic glucose sensing, Microchem. J. 207 (2024) 111833.
[8] E.W. Guo, L. Hao, M.J. Hu, H.Y. Yan, Y.F. Zhang, Synthesis of core-shell structured Cu2O@Co(OH)2 anchored on three-dimensional macroporous carbon for efficient non-enzymatic glucose detection, Microchem. J. 208 (2025) 112319.
[9] R. Ghosh, X. Li, M.Z. Yates, Nonenzymatic glucose sensor using bimetallic catalysts, ACS Appl. Mater. Interfaces 16 (1) (2024) 17-29.
[10] H.H. Shu, L.L. Cao, G. Chang, H.P. He, Y.T. Zhang, Y.B. He, Direct electrodeposition of gold nanostructures onto glassy carbon electrodes for non-enzymatic detection of glucose, Electrochim. Acta 132 (2014) 524-532.
[11] D. Feng, F. Wang, Z.L. Chen, Electrochemical glucose sensor based on one-step construction of gold nanoparticle-chitosan composite film, Sens. Actuat. B Chem. 138 (2) (2009) 539-544.
[12] H. Jeong, J. Kim, Fabrication of nanoporous Au films with ultra-high surface area for sensitive electrochemical detection of glucose in the presence of Cl-, Appl. Surf. Sci. 297 (2014) 84-88.
[13] M. Govindaraj, A. Srivastava, M.K. Muthukumaran, P.C. Tsai, Y.C. Lin, B.K. Raja, J. Rajendran, V.K. Ponnusamy, J. Arockia Selvi, Current advancements and prospects of enzymatic and non-enzymatic electrochemical glucose sensors, Int. J. Biol. Macromol. 253 (Pt 2) (2023) 126680.
[14] P. Subramanian, J. Niedziolka-Jonsson, A. Lesniewski, Q. Wang, M.S. Li, R. Boukherroub, S. Szunerits, Preparation of reduced graphene oxide-Ni(OH)2 composites by electrophoretic deposition: Application for non-enzymatic glucose sensing, J. Mater. Chem. A 2 (15) (2014) 5525-5533.
[15] L.B. Shi, X. Zhu, T.T. Liu, H.L. Zhao, M.B. Lan, Encapsulating Cu nanoparticles into metal-organic frameworks for nonenzymatic glucose sensing, Sens. Actuat. B Chem. 227 (2016) 583-590.
[16] Y.T. Chen, Y.L. Tian, P. Zhu, L.P. Du, W. Chen, C.S. Wu, Electrochemically activated conductive Ni-based MOFs for non-enzymatic sensors toward long-term glucose monitoring, Front. Chem. 8 (2020) 602752.
[17] N. Mohamad Nor, N.S. Ridhuan, K. Abdul Razak, Progress of enzymatic and non-enzymatic electrochemical glucose biosensor based on nanomaterial-modified electrode, Biosensors 12 (12) (2022) 1136.
[18] Y.L. Men, P. Liu, Y. Liu, X.Y. Meng, Y.X. Pan, Noble-metal-free WO3-decorated carbon nanotubes with strong W-C bonds for boosting an electrocatalytic glucose oxidation reaction, Ind. Eng. Chem. Res. 61 (12) (2022) 4300-4309.
[19] S. Dou, L. Tao, R. Wang, S. El Hankari, R. Chen, S. Wang, Plasma-assisted synthesis and surface modification of electrode materials for renewable energy, Adv. Mater. 30 (21) (2018) e1705850.
[20] K.C. Sabat, R.K. Paramguru, B.K. Mishra, Reduction of copper oxide by low-temperature hydrogen plasma, Plasma Chem. Plasma Process. 36 (4) (2016) 1111-1124.
[21] Y. Shu, B. Li, J.Y. Chen, Q. Xu, H. Pang, X.Y. Hu, Facile synthesis of ultrathin nickel-cobalt phosphate 2D nanosheets with enhanced electrocatalytic activity for glucose oxidation, ACS Appl. Mater. Interfaces 10 (3) (2018) 2360-2367.
[22] P. Zhang, J.Y. Fan, Y.Q. Wang, Y.Y. Dang, S. Heumann, Y.X. Ding, Insights into the role of defects on the Raman spectroscopy of carbon nanotube and biomass-derived carbon, Carbon 222 (2024) 118998.
[23] M.R. Rizk, M.G. Abd El-Moghny, Controlled galvanic decoration boosting catalysis: Enhanced glycerol electro-oxidation at Cu/Ni modified macroporous films, Int. J. Hydrog. Energy 46 (1) (2021) 645-655.
[24] R. Akter, P. Saha, S.S. Shah, M.N. Shaikh, M.A. Aziz, A.J.S. Ahammad, Nanostructured nickel-based non-enzymatic electrochemical glucose sensors, Chem. Asian J. 17 (23) (2022) e202200897.
[25] Z.D. Gao, Y.Y. Han, Y.M. Wang, J.W. Xu, Y.Y. Song, One-step to prepare self-organized nanoporous NiO/TiO₂ layers and its use in non-enzymatic glucose sensing, Sci. Rep. 3 (2013) 3323.
[26] H.B. Li, L. Zhang, Y.W. Mao, C.W. Wen, P. Zhao, A simple electrochemical route to access amorphous co-Ni hydroxide for non-enzymatic glucose sensing, Nanoscale Res. Lett. 14 (1) (2019) 135.
[27] N.S. Ismail, Q.H. Le, H. Yoshikawa, M. Saito, E. Tamiya, Development of non-enzymatic electrochemical glucose sensor based on graphene oxide nanoribbon-gold nanoparticle hybrid, Electrochim. Acta 146 (2014) 98-105.
[28] R. Devasenathipathy, V. Mani, S.M. Chen, S.T. Huang, T.T. Huang, C.M. Lin, K.Y. Hwa, T.Y. Chen, B.J. Chen, Glucose biosensor based on glucose oxidase immobilized at gold nanoparticles decorated graphene-carbon nanotubes, Enzyme Microb. Technol. 78 (2015) 40-45.
[29] K.G. Qu, S.Y. Wang, H.Y. Yin, J.Y. Gong, L. Wang, S.J. Wu, Binary (α-β) NiS/PANI nanorods with highly efficient catalytic activity in nonenzymatic glucose fuel cells and sensors, Nano 18 (5) (2023) 2350032.
[30] Y.M. Zhao, Y.H. Jiang, Y. Mo, Y.M. Zhai, J.J. Liu, A.C. Strzelecki, X.F. Guo, C.S. Shan, Boosting electrochemical catalysis and nonenzymatic sensing toward glucose by single-atom Pt supported on Cu@CuO core-shell nanowires, Small 19 (18) (2023) e2207240.
[31] E.M. Almutairi, M.A. Ghanem, A. Al-Warthan, M.R. Shaik, S.F. Adil, A.M. Almutairi, Chemical deposition and exfoliation from liquid crystal template: Nickel/nickel (II) hydroxide nanoflakes electrocatalyst for a non-enzymatic glucose oxidation reaction, Arab. J. Chem. 15 (1) (2022) 103467.
[32] J.Z. Cao, J.H. Yun, N.H. Zhang, Y.M. Wei, H. Yang, Z.L. Xu, Bifunctional Ag@Ni-MOF for high performance supercapacitor and glucose sensor, Synth. Met. 282 (2021) 116931.
[33] A. Cruz-Zabalegui, P. Tirado-Cantu, E.J. Alvarado-Munoz, J.J. Alcantar-Pena, G. Martinez-Saucedo, I.R. Chavez-Urbiola, Microfabricated Ti/Ni electrodes for non-enzymatic glucose detection: Mechanistic insights and interference analysis in blood-mimicking conditions, Talanta 293 (2025) 128050.
[34] Z.J. Wu, N. University, X.M. Xu, N. University, Y. Qi, N. University, N. University, Synthesis of irregular Cu2O nanospheres with remarkable electrocatalytic performance for a nonenzymatic glucose sensor, ACS Appl. Electron. Mater. 7 (5) (2025) 1975-1984.
[35] K.C. Lin, C.Y. Yang, S.M. Chen, Fabrication of a nonenzymatic glucose sensor based on multi-walled carbon nanotubes decorated with platinum and silver hybrid composite, Int. J. Electrochem. Sci. 10 (5) (2015) 3726-3737.
[36] A. Atefi, S. Moradi, F. Salehnia, M. Hosseini, A free enzyme electrochemical glucose sensor using an Integrated display to CeO₂ NPs/Ni MOF-based sensor to highly sensitive Determination of glucose in sweat, Microchem. J. 209 (2025) 112809.
[37] Y.L. Men, N. Dou, Y.Y. Zhao, Y. Huang, L. Zhang, P. Liu, Boosted electrocatalytic glucose oxidation reaction on noble-metal-free MoO3-decorated carbon nanotubes, Trans. Tianjin Univ. 30 (1) (2024) 63-73.

Electrocatalytic glucose oxidation activity of Ni/CNT composites based on low-temperature discharge synthesis

Electrocatalytic glucose oxidation activity of Ni/CNT composites based on low-temperature discharge synthesis

PDF (PC)

Knowledge

Abstract

Cite this article

share this article

References

Related Articles 15

Recommended Articles

Metrics

Comments

[1]	Zhenxing Feng, Bin Song, Zongcheng Zhan, Lei Xu, Hanlei Sun, Shuo Yao, Hongzhi Wang, Licheng Liu. The sulfur and water resistance improvement of Pt/TiO₂ catalyst for CO oxidation reaction by anatase and rutile TiO₂ crystal interfaces [J]. Chinese Journal of Chemical Engineering, 2025, 85(9): 128-139.
[2]	Xintuo Chen, Wencong Chen, Yu Zhou, Liangliang Zhang, Jianfeng Chen. Investigation of reaction pathways and kinetics in the gas-phase noncatalytic oxidation of hexafluoropropylene [J]. Chinese Journal of Chemical Engineering, 2025, 83(7): 286-297.
[3]	Mingqiang Chen, Tingting Zhu, Yishuang Wang, Defang Liang, Chang Li, Haosheng Xin, Jun Wang. Catalytic oxidation of methane for methanol production over copper sepiolite: Effect of noble metals [J]. Chinese Journal of Chemical Engineering, 2025, 82(6): 1-14.
[4]	Zhuolin Yang, Zhenyu Yang, Yanbin Li, Guangwen Chu, Jianfeng Chen. Enhanced degradation of chloramphenicol wastewater in a submerged rotating packed bed reactor: O₃/PDS synergistic oxidation [J]. Chinese Journal of Chemical Engineering, 2025, 82(6): 176-184.
[5]	Shuang Wei, Yingwei Li, Longlong Wang, Kexin Li, Bin He, Ruirui Zhang, Ruixia Liu. Sulfuric acid etching CeO₂ nanoparticles to promote high KA-Oil selectivity in cyclohexane selective oxidation [J]. Chinese Journal of Chemical Engineering, 2025, 81(5): 151-160.
[6]	Xiao Wei, Xuan Fang, Shuming Ma, Huaqiang He, Zhixin Wu, Silin Li, Shihao Zhang, Pei Nian, Wenlan Ji, Yibin Wei. CC/CoNi-LDH anode doped with Ce³⁺ achieving enhanced electrocatalytic oxidation of ciprofloxacin [J]. Chinese Journal of Chemical Engineering, 2025, 80(4): 79-88.
[7]	Jianfang Liu, Hongwei Huang, Jie Yang, Laishuan Liu, Yu Li. Gold nanoparticles on Fe-doped Co₃O₄ for enhanced low-temperature CO oxidation [J]. Chinese Journal of Chemical Engineering, 2025, 78(2): 175-186.
[8]	Zhuo Wang, Zetao Jin, Hanqi Ning, Baishun Jiang, Kaiyuan Xie, Shufeng Zuo, Qiuyan Wang. Study on sulfur resistance of MnO₂/Beta zeolite in toluene catalytic combustion: The effect of increased acidity on catalytic performance [J]. Chinese Journal of Chemical Engineering, 2025, 78(2): 187-195.
[9]	Jialin Chen, Zhenghao Yan, Runxia He, Yanpeng Ban, Huacong Zhou, Quansheng Liu. Structural evolution of iron components and their action behavior on lignite combustion [J]. Chinese Journal of Chemical Engineering, 2025, 78(2): 251-262.
[10]	Wei Cheng, Huilin Wen, Xiaoqiang Chen, Shaobin Zhang, Ziyi Yu. Fluorosurfactants and their application in droplet microreactors: An overview [J]. Chinese Journal of Chemical Engineering, 2025, 78(2): 314-326.
[11]	Yun Zhou, Wenzhi Xia, Guangsheng Wei, Haichuan Wang. Impact of CO₂ as an oxidant on the decarburization and chromium retention and an approach for CO₂ recycling [J]. Chinese Journal of Chemical Engineering, 2025, 77(1): 203-206.
[12]	Jianzhi Wang, Xugen Li, Cheng Zhang, Yuan Pu, Jiawu Liu, Jie Liu, Yanping Liu, Xiao Lin, Faquan Yu. Polygonal mesopores microflower catalysts for the catalytic oxidation of 2-nitro-4-methylsulfonyltoluene to 2-nitro-4-methylsulfonylbenzoic acid in a continuous-flow microreactor [J]. Chinese Journal of Chemical Engineering, 2024, 73(9): 212-221.
[13]	Xin Li, Yue Ma, Xuning Wang, Jianguo Wu, Dong Cao, Daojian Cheng. Regulating the oxidation state of Pd to enhance the selective hydrogenation for 5-hydroxymethylfurfural [J]. Chinese Journal of Chemical Engineering, 2024, 72(8): 60-68.
[14]	Xueqing Ren, Jiahao Niu, Yan Li, Lei Li, Chao Zhang, Qiang Guo, Qiaoling Zhang, Weizhou Jiao. Photocatalytic ozonation-based degradation of phenol by ZnO-TiO₂ nanocomposites in spinning disk reactor [J]. Chinese Journal of Chemical Engineering, 2024, 72(8): 74-84.
[15]	Baichuan Xu, Bin Wang, Tao Li. Four-channel catalytic micro-reactor based on alumina hollow fiber membrane for efficient catalytic oxidation of CO [J]. Chinese Journal of Chemical Engineering, 2024, 71(7): 140-147.