SCI和EI收录∣中国化工学会会刊

中国化学工程学报 ›› 2024, Vol. 72 ›› Issue (8): 95-105.DOI: 10.1016/j.cjche.2024.06.001

• • 上一篇    下一篇

Continuous synthesis of N, N-dicyanoethylaniline in microreactors: Reaction kinetics and process intensification

Pengcheng Lu1, Yaoyao Li1, Jianjun Zhang2, Yuchao Zhao1, Qingqiang Wang1, Ying Chen1, Nan Jin1, Xiugang Yu3   

  1. 1 Shandong Provincial Key Laboratory of Chemical Engineering and Process, College of Chemistry and Chemical Engineering, Yantai University, Yantai 264005, China;
    2 Shandong ANOKY Chemical Technology Research Co., Ltd., Yantai 265601, China;
    3 Yantai Guobang Chemical Machinery Technology Co., Ltd., Yantai 264000, China
  • 收稿日期:2024-02-23 修回日期:2024-06-05 出版日期:2024-08-28 发布日期:2024-10-17
  • 通讯作者: Yuchao Zhao,E-mail:yczhao@ytu.edu.cn;Nan Jin,E-mail:nanjin@ytu.edu.cn
  • 基金资助:
    We gratefully acknowledge the financial supports from National Natural Science Foundation of China (22378344, 22208278), Natural Science Foundation of Shandong Province (ZR2023MB120, ZR2023QB152) and Youth Innovation Team Plan of Shandong Province (2022KJ270).

Continuous synthesis of N, N-dicyanoethylaniline in microreactors: Reaction kinetics and process intensification

Pengcheng Lu1, Yaoyao Li1, Jianjun Zhang2, Yuchao Zhao1, Qingqiang Wang1, Ying Chen1, Nan Jin1, Xiugang Yu3   

  1. 1 Shandong Provincial Key Laboratory of Chemical Engineering and Process, College of Chemistry and Chemical Engineering, Yantai University, Yantai 264005, China;
    2 Shandong ANOKY Chemical Technology Research Co., Ltd., Yantai 265601, China;
    3 Yantai Guobang Chemical Machinery Technology Co., Ltd., Yantai 264000, China
  • Received:2024-02-23 Revised:2024-06-05 Online:2024-08-28 Published:2024-10-17
  • Contact: Yuchao Zhao,E-mail:yczhao@ytu.edu.cn;Nan Jin,E-mail:nanjin@ytu.edu.cn
  • Supported by:
    We gratefully acknowledge the financial supports from National Natural Science Foundation of China (22378344, 22208278), Natural Science Foundation of Shandong Province (ZR2023MB120, ZR2023QB152) and Youth Innovation Team Plan of Shandong Province (2022KJ270).

摘要: Cyanoethylation of phenylamine is one of the important steps for the production of dicyanoethyl-based disperse dyes. However, the exothermic nature of this reaction and the inherent instability of intermittent dynamic operation pose challenges in achieving both high safety and reaction efficiency. In this study, a continuous cyanoethylation of phenylamine for synthesizing N, N-dicyanoethylaniline in a microreactor system has been developed. By optimizing the reaction conditions, the reaction time was significantly reduced from over 2 h in batch operation to approximately 14 min in the microreactor, while high conversion and selectivity were maintained. Based on the reaction network constructed, the reaction kinetics was established, and the kinetic parameters were then determined. These findings provide valuable insights into a controllable cyanoethylation reaction, which would be helpful for the design of efficient processes and optimization of reactors.

关键词: Cyanoethylation, Microreactor, Kinetics, N, N-dicyanoethylaniline, Optimization, Safety

Abstract: Cyanoethylation of phenylamine is one of the important steps for the production of dicyanoethyl-based disperse dyes. However, the exothermic nature of this reaction and the inherent instability of intermittent dynamic operation pose challenges in achieving both high safety and reaction efficiency. In this study, a continuous cyanoethylation of phenylamine for synthesizing N, N-dicyanoethylaniline in a microreactor system has been developed. By optimizing the reaction conditions, the reaction time was significantly reduced from over 2 h in batch operation to approximately 14 min in the microreactor, while high conversion and selectivity were maintained. Based on the reaction network constructed, the reaction kinetics was established, and the kinetic parameters were then determined. These findings provide valuable insights into a controllable cyanoethylation reaction, which would be helpful for the design of efficient processes and optimization of reactors.

Key words: Cyanoethylation, Microreactor, Kinetics, N, N-dicyanoethylaniline, Optimization, Safety