模拟移动床色谱模型的建立及分离纯化大豆卵磷脂

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模拟移动床色谱模型的建立及分离纯化大豆卵磷脂

吕裕斌^a; 危凤^b; 沈波^b; 任其龙^a; 吴平东^a

^a National Laboratory of Secondary Resources Chemical Engineering, Zhejiang University, Hangzhou 310027, China
^b Department of Biological and Pharmaceutical Engineering, Ningbo Institute of Technology, Zhejiang University, Ningbo 315100, China

收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2006-04-28 发布日期:2006-04-28
通讯作者: 吕裕斌

Modeling, Simulation of a Simulated Moving Bed for Separation of Phosphatidylcholine from Soybean Phospholipids

LÜ Yubin^a; WEI Feng^b; SHEN Bo^b; REN Qilong^a;WU Pingdong^a

^a National Laboratory of Secondary Resources Chemical Engineering, Zhejiang University, Hangzhou 310027, China
^b Department of Biological and Pharmaceutical Engineering, Ningbo Institute of Technology, Zhejiang University, Ningbo 315100, China

Received:1900-01-01 Revised:1900-01-01 Online:2006-04-28 Published:2006-04-28
Contact: LÜ Yubin

摘要/Abstract

摘要： A rate model, which considers axial dispersion, external mass transfer, intraparticle diffusion and nonlinear isotherms, and ports periodic switching is adopted to simulate the simulated moving bed (SMB) process. The effects of flow rate in Sections 2 and 3 and switching time on the operating performance parameters: purity, re-covery, productivity and desorbent consumption are studied. A simulation approach is applied to simulate the opera-tion and performance of the SMB. The model predicts the performance of the transient and cyclic steady state be-havior to a reasonably good extent, and provides guidance operation condition of the SMB process.

关键词: simulated moving bed;modeling;simulation;soybean phosphatidylcholine

Abstract: A rate model, which considers axial dispersion, external mass transfer, intraparticle diffusion and nonlinear isotherms, and ports periodic switching is adopted to simulate the simulated moving bed (SMB) process. The effects of flow rate in Sections 2 and 3 and switching time on the operating performance parameters: purity, re-covery, productivity and desorbent consumption are studied. A simulation approach is applied to simulate the opera-tion and performance of the SMB. The model predicts the performance of the transient and cyclic steady state be-havior to a reasonably good extent, and provides guidance operation condition of the SMB process.

Key words: simulated moving bed, modeling, simulation, soybean phosphatidylcholine

吕裕斌, 危凤, 沈波, 任其龙, 吴平东. 模拟移动床色谱模型的建立及分离纯化大豆卵磷脂[J]. , DOI: .

LÜ, Yubin, WEI Feng, SHEN Bo, REN Qilong, WU Pingdong. Modeling, Simulation of a Simulated Moving Bed for Separation of Phosphatidylcholine from Soybean Phospholipids[J]. , DOI: .

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