Aminolysis of ethyl acetate in continuous flow and its reaction kinetics

doi:10.1016/j.cjche.2019.03.015

Chinese Journal of Chemical Engineering ›› 2019, Vol. 27 ›› Issue (12): 2948-2952.DOI: 10.1016/j.cjche.2019.03.015

• Catalysis, kinetics and reaction engineering • Previous Articles Next Articles

Aminolysis of ethyl acetate in continuous flow and its reaction kinetics

Tao Shen¹, Bo Ouyang^1,2, Chao Qian^1,3, Xinzhi Chen¹

1 Zhejiang Provincial Key Laboratory of Advanced Chemical Engineering Manufacture Technology, College of Chemical and Biological Engineering, Zhejiang University, Hangzhou 310027, China;
2 Zhejiang Garden Biochemical High-Tech Co., LTD, Dongyan 322121, China;
3 Research Institute of Zhejiang University-Quzhou, Quzhou 324000, China

Received:2019-01-04 Revised:2019-03-18 Online:2020-03-17 Published:2019-12-28
Contact: Chao Qian
Supported by:
The authors are grateful for the financial support from the National Natural Science Foundation of China (21476194) and the National Key Research and Development Program of China (2016YFB0301800).

Aminolysis of ethyl acetate in continuous flow and its reaction kinetics

Tao Shen¹, Bo Ouyang^1,2, Chao Qian^1,3, Xinzhi Chen¹

1 Zhejiang Provincial Key Laboratory of Advanced Chemical Engineering Manufacture Technology, College of Chemical and Biological Engineering, Zhejiang University, Hangzhou 310027, China;
2 Zhejiang Garden Biochemical High-Tech Co., LTD, Dongyan 322121, China;
3 Research Institute of Zhejiang University-Quzhou, Quzhou 324000, China

通讯作者: Chao Qian
基金资助:
The authors are grateful for the financial support from the National Natural Science Foundation of China (21476194) and the National Key Research and Development Program of China (2016YFB0301800).

Abstract

Abstract: The aminolysis of ethyl acetate was promoted significantly via continuous reaction in a tubular reactor. N-propylacetamide was thus synthesized without presence of solvent and catalyst. The optimum conditions were obtained as follows:the reaction temperature is 218℃, the reaction pressure is 3.5 MPa, the molar ratio (ethyl acetate:N-propylamine) is 1:1, and the residence time is 350 min. Accordingly, the conversion of ethyl acetate is up to 94.8%. Furthermore, the kinetics of the rapid reaction stage (when the conversion of ethyl acetate is 20%-80%) can be expressed as lnk--4629:44 1/T + 2:1366, and the apparent activation energy is E_a=38489 J·mol^-1.

Key words: Tubular reactor, Reaction kinetics, Ethyl acetate, Aminolysis

摘要： The aminolysis of ethyl acetate was promoted significantly via continuous reaction in a tubular reactor. N-propylacetamide was thus synthesized without presence of solvent and catalyst. The optimum conditions were obtained as follows:the reaction temperature is 218℃, the reaction pressure is 3.5 MPa, the molar ratio (ethyl acetate:N-propylamine) is 1:1, and the residence time is 350 min. Accordingly, the conversion of ethyl acetate is up to 94.8%. Furthermore, the kinetics of the rapid reaction stage (when the conversion of ethyl acetate is 20%-80%) can be expressed as lnk--4629:44 1/T + 2:1366, and the apparent activation energy is E_a=38489 J·mol^-1.

关键词: Tubular reactor, Reaction kinetics, Ethyl acetate, Aminolysis

Tao Shen, Bo Ouyang, Chao Qian, Xinzhi Chen. Aminolysis of ethyl acetate in continuous flow and its reaction kinetics[J]. Chinese Journal of Chemical Engineering, 2019, 27(12): 2948-2952.

Tao Shen, Bo Ouyang, Chao Qian, Xinzhi Chen. Aminolysis of ethyl acetate in continuous flow and its reaction kinetics[J]. 中国化学工程学报, 2019, 27(12): 2948-2952.

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Aminolysis of ethyl acetate in continuous flow and its reaction kinetics

Aminolysis of ethyl acetate in continuous flow and its reaction kinetics

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