SCI和EI收录∣中国化工学会会刊

›› 2009, Vol. 17 ›› Issue (5): 875-878.

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Hydrotalcite-like Materials as Catalyst for the Conjugate Addition of Amines to Electron Deficient Alkenes

陈露1, 朱娟1, 王箭1, 吴海虹1, 杨建国1,2   

  1. 1. Key Laboratory of Green Chemistry and Chemical Process, Department of Chemistry, East China Normal University, Shanghai 200062, China;
    2. Energy Institue, Department of Materials Science and Engineering, Pennsylvania State University, University Park, PA 16802, USA
  • 收稿日期:2009-03-05 修回日期:2009-07-28 出版日期:2009-10-28 发布日期:2009-10-28
  • 通讯作者: YANG Jianguo,E-mail:jgyang@chem.ecnu.edu.cn;jzy2@psu.edu
  • 基金资助:
    Supported by the National Key Project of Scientific and Technical Supporting Programs Funded by Ministry of Science & Technology of China (2006BAE03B06);Shanghai Leading Academic Discipline Project (B409);Shanghai International Cooperation of Science and Technology Project (06SR07101)

Hydrotalcite-like Materials as Catalyst for the Conjugate Addition of Amines to Electron Deficient Alkenes

CHEN Lu1, ZHU Juan1, WANG Jian1, WU Haihong1, YANG Jianguo1,2   

  1. 1. Key Laboratory of Green Chemistry and Chemical Process, Department of Chemistry, East China Normal University, Shanghai 200062, China;
    2. Energy Institue, Department of Materials Science and Engineering, Pennsylvania State University, University Park, PA 16802, USA
  • Received:2009-03-05 Revised:2009-07-28 Online:2009-10-28 Published:2009-10-28
  • Supported by:
    Supported by the National Key Project of Scientific and Technical Supporting Programs Funded by Ministry of Science & Technology of China (2006BAE03B06);Shanghai Leading Academic Discipline Project (B409);Shanghai International Cooperation of Science and Technology Project (06SR07101)

摘要: The novel efficient procedure has been developed for the conjugate addition of amines to electron deficient alkenes.A series of hydrotalcite-like materials were synthesized as catalyst for the conjugate addition of amines and alkenes.After optimizing the reaction conditions,ZnAl-LDHs (3:1) was chosen as the best catalyst for the reaction.The results showed that the catalyst worked very well for the conjugate addition of amines to electron deficient alkenes with the excellent yields in several minutes.Operational simplicity,no solvent,low cost of the catalyst,high yields,reusability,excellent chemoselectivity,wide applicability are the key features of this method.

关键词: hydrotalcite-like material, conjugate addition, chemoselectivity, solvent-free synthesis

Abstract: The novel efficient procedure has been developed for the conjugate addition of amines to electron deficient alkenes.A series of hydrotalcite-like materials were synthesized as catalyst for the conjugate addition of amines and alkenes.After optimizing the reaction conditions,ZnAl-LDHs (3:1) was chosen as the best catalyst for the reaction.The results showed that the catalyst worked very well for the conjugate addition of amines to electron deficient alkenes with the excellent yields in several minutes.Operational simplicity,no solvent,low cost of the catalyst,high yields,reusability,excellent chemoselectivity,wide applicability are the key features of this method.

Key words: hydrotalcite-like material, conjugate addition, chemoselectivity, solvent-free synthesis