Measurement and Correlation for Solubility of Diosgenin in Some Mixed Solvents

doi:10.1016/S1004-9541(14)60023-9

Chinese Journal of Chemical Engineering ›› 2014, Vol. 22 ›› Issue (2): 170-176.DOI: 10.1016/S1004-9541(14)60023-9

Measurement and Correlation for Solubility of Diosgenin in Some Mixed Solvents

陈飞雄¹, 赵明蕊², 冯露¹, 任保增¹

1 College of Chemical Engineering and Energy, Zhengzhou University, Zhengzhou 450001, China;
2 Henan Medical College for Staff and Workers, Zhengzhou 451191, China

收稿日期:2012-04-26 修回日期:2012-11-02 出版日期:2014-02-05 发布日期:2014-01-28
通讯作者: REN Baozeng
基金资助:
Supported by Science and Technology Breakthrough Major Project in Henan Province (112101210200).

Measurement and Correlation for Solubility of Diosgenin in Some Mixed Solvents

CHEN Feixiong¹, ZHAO Mingrui², FENG Lu¹, REN Baozeng¹

1 College of Chemical Engineering and Energy, Zhengzhou University, Zhengzhou 450001, China;
2 Henan Medical College for Staff and Workers, Zhengzhou 451191, China

Received:2012-04-26 Revised:2012-11-02 Online:2014-02-05 Published:2014-01-28
Contact: REN Baozeng
Supported by:
Supported by Science and Technology Breakthrough Major Project in Henan Province (112101210200).

摘要/Abstract

摘要： The solubility data of diosgenin in mixed systems of ethanol + 1-propanol (1:1), ethanol + 1-butanol (1:1), ethanol + isobutyl alcohol (1:1), methanol + isobutyl alcohol (1:1), methanol + isobutyl alcohol (1:4), ethanol + 1-pentanol (1:1) and carbon tetrachloride were measured over the temperature range from 289.15 K to 334.15 K by a laser monitoring observation technique at atmospheric pressure, with all mixtures mixed by volume ratio. The Apelblat equation, the ideal solution model, and the λh equation are used to correlate the solubility data. The results show that the three models agree well with the experimental data, providing essential support for industrial design and further theoretical study.

关键词: solid-liquid equilibrium, solubility, diosgenin

Abstract: The solubility data of diosgenin in mixed systems of ethanol + 1-propanol (1:1), ethanol + 1-butanol (1:1), ethanol + isobutyl alcohol (1:1), methanol + isobutyl alcohol (1:1), methanol + isobutyl alcohol (1:4), ethanol + 1-pentanol (1:1) and carbon tetrachloride were measured over the temperature range from 289.15 K to 334.15 K by a laser monitoring observation technique at atmospheric pressure, with all mixtures mixed by volume ratio. The Apelblat equation, the ideal solution model, and the λh equation are used to correlate the solubility data. The results show that the three models agree well with the experimental data, providing essential support for industrial design and further theoretical study.

Key words: solid-liquid equilibrium, solubility, diosgenin

陈飞雄, 赵明蕊, 冯露, 任保增. Measurement and Correlation for Solubility of Diosgenin in Some Mixed Solvents[J]. Chinese Journal of Chemical Engineering, 2014, 22(2): 170-176.

CHEN Feixiong, ZHAO Mingrui, FENG Lu, REN Baozeng. Measurement and Correlation for Solubility of Diosgenin in Some Mixed Solvents[J]. Chin.J.Chem.Eng., 2014, 22(2): 170-176.

参考文献

1 Liu, L., Dong, Y.S., Xiu, Z.L., "Three-liquid-phase extraction of diosgenin and steroidal saponins from fermentation of Dioscorea zingibernsis C. H. Wright", Process Biochemistry, 45,752-756 (2010).

2 Peng, Y.E., Wang, Y.X., Yang, Z.H., Bao, J.G., Hon, Y., "A two-stage nanofiltration process for reclamation of diosgenin wastewater", Desalination, 257, 53-57 (2010).

3 Fernandes, P., Cruz, A., Angelova, B., Pinheiro, H.M., Cabral, J.M.S., "Microbial conversion of steroid compounds: recent developments", Enzyme Microb. Technol., 32, 688-705 (2003).

4 Saunders, R., Cheetham, P.S.J., Hardman, R., "Microbial transfor-mation of crude fenugreek steroids", Enzyme Microb. Technol., 8, 549-555 (1986).

5 Chen, F.X., Zhao, M.R., Ren, B.Z., Zhou, C.R., Peng, F.F., "Solubility of diosgenin in different solvents", J. Chem. Thermodyn., 47, 341-346 (2012).

6 Chen, F.X., Zhao, M.R., Liu, C.C., Peng, F.F., Ren, B.Z., "Determination and correlation of the solubility for diosgenin in alcohol solvents ", J. Chem. Thermodyn., 50, 1-6 (2012).

7 Zhou, C.R., Shi, X.H., Wang, H.F., "Measurement and correlation of solubilities of trans-ferulic acid in solvents", J. Chem. Ind. Eng. (China), 58, 2705-2709 (2007). (in Chinese)

8 Buchowski, H., Ksiazczak, A., Pietrzyk, S., "Solvent activity along a saturation line and solubility of hydrogen bonding solid", J. Phys. Chem., 84, 975-979 (1980).

9 Liu, G.Q., Ma, L.X., Liu, J., Manual of Chemical and Physical Properties (Organic Volume), Chemical Industry Press, Beijing (2002).

10 Apelblat, A, Manzurola, E., "Solubilities of o-acetylsalicylic, 3,5-dinit rosalicylic, and p-toluic acid, and magnesium DL aspartate in water from T (278 to 348) K", J. Chem. Thermodyn., 31, 85-91 (1999).

11 Stanley, M.W., Phase Equilibria in Chemical Engineering, Butter-worth, New York (1985).

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Measurement and Correlation for Solubility of Diosgenin in Some Mixed Solvents

Measurement and Correlation for Solubility of Diosgenin in Some Mixed Solvents

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