An efficient microreactor with continuous serially connected micromixers for the synthesis of superparamagnetic magnetite nanoparticles

doi:10.1016/j.cjche.2022.12.008

Chinese Journal of Chemical Engineering ›› 2023, Vol. 59 ›› Issue (7): 85-91.DOI: 10.1016/j.cjche.2022.12.008

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An efficient microreactor with continuous serially connected micromixers for the synthesis of superparamagnetic magnetite nanoparticles

Wenting Fan¹, Fang Zhao¹, Ming Chen¹, Jian Li¹, Xuhong Guo^1,2

1. State Key Laboratory of Chemical Engineering, School of Chemical Engineering, East China University of Science and Technology, Shanghai 200237, China;
2. International Joint Research Center of Green Energy Chemical Engineering, Shanghai 200237, China

Received:2022-08-21 Revised:2022-12-23 Online:2023-10-14 Published:2023-07-28
Contact: Fang Zhao,E-mail:fzhao1@ecust.edu.cn;Xuhong Guo,E-mail:guoxuhong@ecust.edu.cn
Supported by:
We gratefully thank the financial support from the National Natural Science Foundation of China (21808059) and the Fundamental Research Funds for the Central Universities (JKA01221712).

An efficient microreactor with continuous serially connected micromixers for the synthesis of superparamagnetic magnetite nanoparticles

Wenting Fan¹, Fang Zhao¹, Ming Chen¹, Jian Li¹, Xuhong Guo^1,2

1. State Key Laboratory of Chemical Engineering, School of Chemical Engineering, East China University of Science and Technology, Shanghai 200237, China;
2. International Joint Research Center of Green Energy Chemical Engineering, Shanghai 200237, China

通讯作者: Fang Zhao,E-mail:fzhao1@ecust.edu.cn;Xuhong Guo,E-mail:guoxuhong@ecust.edu.cn
基金资助:
We gratefully thank the financial support from the National Natural Science Foundation of China (21808059) and the Fundamental Research Funds for the Central Universities (JKA01221712).

Abstract

Abstract: A new microreactor with continuous serially connected micromixers (CSCM) was tailored for the coprecipitation process to synthesize Fe₃O₄ nanoparticles. Numerical simulation reveals that the two types of CSCM microchannels (V-typed and U-typed) proposed in this work exhibited markedly better mixing performances than the Zigzag and capillary microchannels due to the promotion of Dean vortices. Complete mixing was achieved in the V-typed microchannel in 2.7 s at an inlet Reynolds number of 27. Fe₃O₄ nanoparticles synthesized in a planar glass microreactor with the V-typed microchannel, possessing an average size of 9.3 nm and exhibiting superparamagnetism, had obviously better dispersity and uniformity and higher crystallinity than those obtained in the capillary microreactor. The new CSCM microreactor developed in this work can act as a potent device to intensify the synthesis of similar inorganic nanoparticles via multistep chemical precipitation processes.

Key words: Microreactor, Continuous serially connected micromixers, Mixing, Nanoparticles

摘要： A new microreactor with continuous serially connected micromixers (CSCM) was tailored for the coprecipitation process to synthesize Fe₃O₄ nanoparticles. Numerical simulation reveals that the two types of CSCM microchannels (V-typed and U-typed) proposed in this work exhibited markedly better mixing performances than the Zigzag and capillary microchannels due to the promotion of Dean vortices. Complete mixing was achieved in the V-typed microchannel in 2.7 s at an inlet Reynolds number of 27. Fe₃O₄ nanoparticles synthesized in a planar glass microreactor with the V-typed microchannel, possessing an average size of 9.3 nm and exhibiting superparamagnetism, had obviously better dispersity and uniformity and higher crystallinity than those obtained in the capillary microreactor. The new CSCM microreactor developed in this work can act as a potent device to intensify the synthesis of similar inorganic nanoparticles via multistep chemical precipitation processes.

关键词: Microreactor, Continuous serially connected micromixers, Mixing, Nanoparticles

Wenting Fan, Fang Zhao, Ming Chen, Jian Li, Xuhong Guo. An efficient microreactor with continuous serially connected micromixers for the synthesis of superparamagnetic magnetite nanoparticles[J]. Chinese Journal of Chemical Engineering, 2023, 59(7): 85-91.

References

[1] A.K. Gupta, M. Gupta, Synthesis and surface engineering of iron oxide nanoparticles for biomedical applications, Biomaterials 26 (18) (2005) 3995-4021.
[2] M.F. Shao, F.Y. Ning, J.W. Zhao, M. Wei, D.G. Evans, X. Duan, Preparation of Fe₃O₄@SiO₂@layered double hydroxide core-shell microspheres for magnetic separation of proteins, J. Am. Chem. Soc. 134 (2) (2012) 1071-1077.
[3] S. Chatterjee, X.S. Li, F. Liang, Y.W. Yang, Design of multifunctional fluorescent hybrid materials based on SiO₂ materials and core-shell Fe₃O₄@SiO₂ nanoparticles for metal ion sensing, Small 15 (44) (2019) 1904569.
[4] S.C.N. Tang, I.M.C. Lo, Magnetic nanoparticles: Essential factors for sustainable environmental applications, Water Res. 47 (8) (2013) 2613-2632.
[5] Y.D. Zou, B.T. Huang, L.H. Cao, Y.H. Deng, J.C. Su, Tailored mesoporous inorganic biomaterials: Assembly, functionalization, and drug delivery engineering, Adv. Mater. 33 (2) (2021) e2005215.
[6] C. Chingakham, A. David, V. Sajith, Fe₃O₄ nanoparticles impregnated eggshell as a novel catalyst for enhanced biodiesel production, Chin. J. Chem. Eng. 27 (11) (2019) 2835-2843.
[7] S.L. Gai, P.P. Yang, C.X. Li, W.X. Wang, Y.L. Dai, N. Niu, J. Lin, Synthesis of magnetic, up-conversion luminescent, and mesoporous core-shell-structured nanocomposites as drug carriers, Adv. Funct. Mater. 20 (7) (2010) 1166-1172.
[8] J. Xu, H.B. Yang, W.Y. Fu, K. Du, Y.M. Sui, J.J. Chen, Y. Zeng, M.H. Li, G.T. Zou, Preparation and magnetic properties of magnetite nanoparticles by sol-gel method, J. Magn. Magn. Mater. 309 (2) (2007) 307-311.
[9] L.G. Yan, S. Li, H.Q. Yu, R.R. Shan, B. Du, T.T. Liu, Facile solvothermal synthesis of Fe₃O₄/bentonite for efficient removal of heavy metals from aqueous solution, Powder Technol. 301 (2016) 632-640.
[10] J. Shan, L. Wang, H. Yu, J. Ji, W.A. Amer, Y. Chen, G. Jing, H. Khalid, M. Akram, N.M. Abbasi, Recent progress in Fe₃O₄ based magnetic nanoparticles: From synthesis to application, Mater. Sci. Technol. 32 (2016) 602-614.
[11] R.K. Sharma, S. Dutta, S. Sharma, R. Zboril, R.S. Varma, M.B. Gawande, Fe₃O₄ (iron oxide)-supported nanocatalysts: Synthesis, characterization and applications in coupling reactions, Green Chem. 18 (11) (2016) 3184-3209.
[12] J.S. Sui, J.Y. Yan, D. Liu, K. Wang, G.S. Luo, Continuous synthesis of nanocrystals via flow chemistry technology, Small 17 (33) (2021) e2104166.
[13] S. Marre, K.F. Jensen, Synthesis of micro and nanostructures in microfluidic systems, Chem. Soc. Rev. 39 (3) (2010) 1183-1202.
[14] G. Salazar-Alvarez, M. Muhammed, A.A. Zagorodni, Novel flow injection synthesis of iron oxide nanoparticles with narrow size distribution, Chem. Eng. Sci. 61 (14) (2006) 4625-4633.
[15] A.M. Nightingale, J.C. Demello, Segmented flow reactors for nanocrystal synthesis, Adv. Mater. 25 (13) (2013) 1813-1821.
[16] A.G. Niculescu, C. Chircov, A.C. Bîrcă, A.M. Grumezescu, Nanomaterials synthesis through microfluidic methods: An updated overview, Nanomaterials 11 (4) (2021) 864.
[17] V. Hakke, S. Sonawane, S. Anandan, S. Sonawane, M. Ashokkumar, Process intensification approach using microreactors for synthesizing nanomaterials—A critical review, Nanomaterials 11 (1) (2021) 98.
[18] P. Zardi, T. Carofiglio, M. Maggini, Mild microfluidic approaches to oxide nanoparticles synthesis, Chemistry 28 (9) (2022) e202103132.
[19] S. Lin, K.F. Lin, D.N. Lu, Z. Liu, Preparation of uniform magnetic iron oxide nanoparticles by co-precipitation in a helical module microchannel reactor, J. Environ. Chem. Eng. 5 (1) (2017) 303-309.
[20] T.H. Gu, Y.F. Zhang, S.A. Khan, T.A. Hatton, Continuous flow synthesis of superparamagnetic nanoparticles in reverse miniemulsion systems, Colloid Interface Sci. Commun. 28 (2019) 1-4.
[21] F. Vereda, J. de Vicente, R. Hidalgo-Alvarez, Influence of a magnetic field on the formation of magnetite particles via two precipitation methods, Langmuir 23 (7) (2007) 3581-3589.
[22] T. Ahn, J.H. Kim, H.M. Yang, J.W. Lee, J.D. Kim, Formation pathways of magnetite nanoparticles by coprecipitation method, J. Phys. Chem. C 116 (10) (2012) 6069-6076.
[23] G. Gnanaprakash, S. Mahadevan, T. Jayakumar, P. Kalyanasundaram, J. Philip, B. Raj, Effect of initial pH and temperature of iron salt solutions on formation of magnetite nanoparticles, Mater. Chem. Phys. 103 (1) (2007) 168-175.
[24] M.C. Mascolo, Y. Pei, T.A. Ring, Room temperature co-precipitation synthesis of magnetite nanoparticles in a large pH window with different bases, Materials 6 (12) (2013) 5549-5567.
[25] N. Nivedita, P. Ligrani, I. Papautsky, Dean flow dynamics in low-aspect ratio spiral microchannels, Sci. Rep. 7 (2017) 44072.

An efficient microreactor with continuous serially connected micromixers for the synthesis of superparamagnetic magnetite nanoparticles

An efficient microreactor with continuous serially connected micromixers for the synthesis of superparamagnetic magnetite nanoparticles

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