Liquid-Liquid-Liquid Three Phase Extraction Apparatus:Operation Strategy and Influences on Mass Transfer Efficiency

›› 2012, Vol. 20 ›› Issue (1): 27-35.

Liquid-Liquid-Liquid Three Phase Extraction Apparatus:Operation Strategy and Influences on Mass Transfer Efficiency

何秀琼^1,2, 黄昆¹, 于品华^1,2, 张超^1,2, 谢铿^1,2, 李鹏飞^1,2, 王娟^1,2, 安震涛¹, 刘会洲¹

1. Key Laboratory of Green Process and Engineering, Institute of Process Engineering, Chinese Academy of Sci-ences, Beijing 100190, China;
2. Graduate University of Chinese Academy of Sciences, Beijing 100049, China

收稿日期:2011-06-28 修回日期:2011-09-23 出版日期:2012-02-28 发布日期:2012-05-03
通讯作者: HUANG Kun,E-mail:khuang@home.ipe.ac.cn;LIU Huizhou,E-mail:hzliu@home.ipe.ac.cn
基金资助:
Supported by the National Natural Science Foundation of China (51074150,21027004);the National Basic Research Program of China (2012CBA01203,2007CB613507);the Innovative Research Group Science Fund (20221603)

Liquid-Liquid-Liquid Three Phase Extraction Apparatus:Operation Strategy and Influences on Mass Transfer Efficiency

HE Xiuqiong^1,2, HUANG Kun¹, YU Pinhua^1,2, ZHANG Chao^1,2, XIE Keng^1,2, LI Pengfei^1,2, WANG Juan^1,2, AN Zhentao¹, LIU Huizhou¹

1. Key Laboratory of Green Process and Engineering, Institute of Process Engineering, Chinese Academy of Sci-ences, Beijing 100190, China;
2. Graduate University of Chinese Academy of Sciences, Beijing 100049, China

Received:2011-06-28 Revised:2011-09-23 Online:2012-02-28 Published:2012-05-03
Supported by:
Supported by the National Natural Science Foundation of China (51074150,21027004);the National Basic Research Program of China (2012CBA01203,2007CB613507);the Innovative Research Group Science Fund (20221603)

摘要/Abstract

摘要： A new mixer-settler-mixer three chamber integrated extractor is proposed in this work for liquid-liquid-liquid three phase countercurrent and continuous extraction.Experiments revealed the influences of the structural design of the three-liquid-phase extractor and some key operational parameters on three-phase partition of two phenolic isomers,p-nitrophenol(p-NP) and o-nitrophenol(o-NP).The model three-liquid-phase extraction system used here is nonane(organic top-phase)-polyethylene glycol(PEG 2000)(polymer middle-phase)-(NH₄)₂SO₄ aqueous solution(aqueous bottom-phase).It is indicated that agitating speed and retention time in three-phase mixer are key parameters to extraction fraction of nitrophenol.Dispersion band behavior is related to agitating intensity,and its occurrence does not affect the extraction fraction of target compounds.The present work highlights the possibility of a feasible approach of scaling up of the proposed three-phase extraction apparatus for future industrial-aimed applications.

关键词: three-liquid-phase extraction, extractor, mixer-settler-mixer, separation, nitrophenol

Abstract: A new mixer-settler-mixer three chamber integrated extractor is proposed in this work for liquid-liquid-liquid three phase countercurrent and continuous extraction.Experiments revealed the influences of the structural design of the three-liquid-phase extractor and some key operational parameters on three-phase partition of two phenolic isomers,p-nitrophenol(p-NP) and o-nitrophenol(o-NP).The model three-liquid-phase extraction system used here is nonane(organic top-phase)-polyethylene glycol(PEG 2000)(polymer middle-phase)-(NH₄)₂SO₄ aqueous solution(aqueous bottom-phase).It is indicated that agitating speed and retention time in three-phase mixer are key parameters to extraction fraction of nitrophenol.Dispersion band behavior is related to agitating intensity,and its occurrence does not affect the extraction fraction of target compounds.The present work highlights the possibility of a feasible approach of scaling up of the proposed three-phase extraction apparatus for future industrial-aimed applications.

Key words: three-liquid-phase extraction, extractor, mixer-settler-mixer, separation, nitrophenol

中图分类号:

TQ028.32

何秀琼, 黄昆, 于品华, 张超, 谢铿, 李鹏飞, 王娟, 安震涛, 刘会洲. Liquid-Liquid-Liquid Three Phase Extraction Apparatus:Operation Strategy and Influences on Mass Transfer Efficiency[J]. , 2012, 20(1): 27-35.

HE Xiuqiong, HUANG Kun, YU Pinhua, ZHANG Chao, XIE Keng, LI Pengfei, WANG Juan, AN Zhentao, LIU Huizhou. Liquid-Liquid-Liquid Three Phase Extraction Apparatus:Operation Strategy and Influences on Mass Transfer Efficiency[J]. , 2012, 20(1): 27-35.

参考文献

1 Mojski,M.,Gluch,I.,"Characteristics and applications of three-phase extraction systems",J.Anal Chem.,51,329-342(1996).
2 Chen,J.,Liu,H.Z.,Wang,B.,"Study on the three-phase extraction of penicillin G with a single step method",In:Proceedings of the Conference on Solvent Extraction(ISEC2002),Cape Town,602-606(2002).
3 Da Silva,L.H.M.,Loh,W.,"Polymer induced multiphase generation in water/organic solvent mixtures.Strategies towards the design of triphasic and tetraphasic liquid systems",Chem.Commun.,7,787-788(1998).
4 Palma,M.S.A.,Shibata,C.,Paiva,J.L.,Zilli,M.,Converti,A.,"Batch liquid-liquid extraction of phenol from aqueous solutions",Chem.Eng.Technol.,33(1),39-43(2010).
5 Palma,M.S.A.,Paiva,J.L.,Zilli,M.,Converti,A.,"Batch phenol removal from methyl isobutyl ketone by liquid-liquid extraction with chemical reaction",Chem.Eng.Process.,46,764-768(2007).
6 Jiang,H.,Fang,Y.,Fu,Y.,Guo,Q.X.,"Studies on the extraction of phenol in wastewater",J.Hazard.Mater.,B101,179-190(2003).
7 Deng,T.,Huang,L.J.,Fu,L.,"Synergistic extraction of gallium from sulfate solution",Chin.J.Chem.Eng.,10(1),112-115(2002).
8 Xie,K.,Zhao,J.M.,Yang,L.R.,Yu,P.H.,Liu,H.Z.,"Investigation of three-liquid-phase extraction systems for the separation of Ti(Ⅳ),Fe(Ⅲ)and Mg(Ⅱ)",Sep.Purif.Technol.,76,191-197(2010).
9 Xie,K.,Huang,K.,Xu,L.,Yu,P.H.,Yang,L.R.,Liu,H.Z.,"Three-liquid-phase extraction and separation of Ti(Ⅳ),Fe(Ⅲ),and Mg(Ⅱ)",Ind.Eng.Chem.Res.,50,6362-6368(2011).
10 Merchuk,J.C.,Andrews,B.A.,Asenjo,J.A.,"Aqueous two-phase systems for protein separation Studies on phase inversion",J.Phys. Chem.B,711,285-293(1998).
11 Huddleston,J.G.,Willauer,H.D.,Griffin,S.T.,Rogers,R.D.,"Aqueous polymeric solutions as environmentally benign liquid/liquid extraction media",Ind.Eng.Chem.Res.,38,2523-2539 (1999).
12 Nandini,K.E.,Rastogi,N.K.,"Liquid-liquid extraction of lipase using aqueous two-phase system",Food Bioprocess Technol.,4,295-303(2011).
13 Hu,Z.,Hu,X.,Cui,W.,Wang,D.,Fu,X.,"Three phase extraction study.Ⅱ.TBP-kerosene/H₂SO₄-TiOSO₄ system and the preparation of ultrafine powder of TiO₂",Colloids Surf.A,155,383-393(1999).
14 Shen,S.F.,Chang,Z.D.,Sun,X.H.,Liu,H.Z.,"Process integration for production of 6-aminnopenicillanic acid from penicillin G fermentation broth",Process Biochem.,41,571-574(2006).
15 Jiang,Y.Y.,Xia,H.S.,Guo,C.,Mahmood,I.,Liu,H.Z.,"Enzymatic hydrolysis of penicillin for 6-APA production in three-liquid-phase system",Appl.Biochem.Biotechnol.,144,145-159(2008).
16 Shen,S.F.,Chang,Z.D.,Liu,H.Z.,"Three-liquid-phase extraction systems for separation of phenol and p-nitrophenol from wastewater",Sep.Purif.Technol.,49,217-222(2006).
17 Shen,S.F.,Chang,Z.D.,Liu,J.,Sun,X.H.,Hu,X.,Liu,H.Z.,"Separation of glycyrrhizic acid and liquiritin from glycyrrhiza uralensis fisch extract by three-liquid-phase extraction systems",Sep. Purif.Technol.,53,216-223(2007).
18 Gaur,R.,Sharma,A.,Khare,S.K.,Gupta,N.M.,"A novel process for extraction of edible oils enzyme assisted three phase partitioning (EATPP)",Bioresour.Technol.,98,696-699(2007).
19 Liu,L.,Dong,Y.S.,Xiu,Z.L.,"Three-liquid-phase extraction of diosgenin and steroidal saponins from fermentation of Dioscorea zingibernsis C.H.Wright",Process Biochem.,45,752-756(2010).
20 Yu,P.H.,Chang,Z.D.,Ma,Y.C.,Wang,S.J.,Cao,H.B.,Hua,C.,Liu,H.Z.,"Separation of p-nitrophenol and o-nitrophenol with three-liquid-phase extraction system",Sep.Purif.Technol.,70,199-206(2009).
21 Wang,J.D.,Chen,J.Y.,Solvent Extraction Manual,Chemical Industry Press,Beijing,180-395(2001).(in Chinese)
22 Zhou,J.Z.,Duan,W.H.,Xu,J.Q.,Yang,Y.Y.,"Experimental and simulation study on the extraction of p-cresol using centrifugal extractors",Chin.J.Chem.Eng.,15(2),209-214(2007).
23 Ren,X.G.,Song,Y.J.,"A study on a gas agitated extractor with static mixer",Chin.J.Chem.Eng.,6(4),361-365(1998).
24 Tang,X.J.,Luo,G.S.,Wang,J.D.,"Mass transfer and axial mixing characteristic in a coalescence-dispersion pulsed-sieve-plate extraction column",Chin.J.Chem.Eng.,12(6),857-861(2004).
25 Khakpay,A.,Abolghasemi,H.,"The effects of impeller speed and holdup on mean drop size in a mixer settler with spiral-type impeller",Can.J.Chem.Eng.,88,329-334(2010).
26 Chen,Z.,Pruss,J.,Warnecke,H.J.,"A population balance model for disperse systems:Drop size distribution in emulsion",Chem.Eng. Sci.,53,1059-1066(1998).
27 Jeelani,S.A.K.,Hartland,S.,"Prediction of steady state height from batch settling dispersion data",AlChE J.,31(5),711-720(1985).
28 Jeelani,S.A.K.,Hartland,S.,"Dynamic response of gravity settlers to changes in dispersion throughput",AIChE J.,34(2),335-340 (1988).
29 Rajni,H.K.,"Aqueous two-phase systems",Mol.Biotechnol.,19,269-277(2001).

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Liquid-Liquid-Liquid Three Phase Extraction Apparatus:Operation Strategy and Influences on Mass Transfer Efficiency

Liquid-Liquid-Liquid Three Phase Extraction Apparatus:Operation Strategy and Influences on Mass Transfer Efficiency

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