SCI和EI收录∣中国化工学会会刊

Chinese Journal of Chemical Engineering ›› 2018, Vol. 26 ›› Issue (7): 1493-1498.DOI: 10.1016/j.cjche.2018.01.015

• Catalysis, Kinetics and Reaction Engineering • 上一篇    下一篇

Selective aerobic oxidation of p-cresol with co-catalysts between metalloporphyrins and metal salts

Yuanbin She1, Yao Fan1, Lei Zhang1, Ying Xu1, Min Yu1, Haiyan Fu2   

  1. 1 State Key Laboratory Breeding Base of Green Chemistry-Synthesis Technology, College of Chemical Engineering, Zhejiang University of Technology, Hangzhou 310032, China;
    2 The Modernization Engineering Technology Research Center of Ethnic Minority Medicine of Hubei Province, School of Pharmaceutical Sciences, South Central University for Nationalities, Wuhan 430074, China
  • 收稿日期:2017-11-02 修回日期:2017-12-28 出版日期:2018-07-28 发布日期:2018-08-16
  • 通讯作者: Yuanbin She,E-mail addresses:sheyb@zjut.edu.cn;Haiyan Fu,E-mail addresses:fuhaiyan@mail.scuec.edu.cn
  • 基金资助:

    Supported by the National Natural Science Foundation of China (21776259, 21776321, 21706233, 21576297, 21476270).

Selective aerobic oxidation of p-cresol with co-catalysts between metalloporphyrins and metal salts

Yuanbin She1, Yao Fan1, Lei Zhang1, Ying Xu1, Min Yu1, Haiyan Fu2   

  1. 1 State Key Laboratory Breeding Base of Green Chemistry-Synthesis Technology, College of Chemical Engineering, Zhejiang University of Technology, Hangzhou 310032, China;
    2 The Modernization Engineering Technology Research Center of Ethnic Minority Medicine of Hubei Province, School of Pharmaceutical Sciences, South Central University for Nationalities, Wuhan 430074, China
  • Received:2017-11-02 Revised:2017-12-28 Online:2018-07-28 Published:2018-08-16
  • Contact: Yuanbin She,E-mail addresses:sheyb@zjut.edu.cn;Haiyan Fu,E-mail addresses:fuhaiyan@mail.scuec.edu.cn
  • Supported by:

    Supported by the National Natural Science Foundation of China (21776259, 21776321, 21706233, 21576297, 21476270).

摘要: A green and efficient method for the selective aerobic oxidation of p-cresol to p-hydroxybenzaldehyde catalyzed by co-catalysts between metalloporphyrins and metal salts was investigated and developed. The relationship between the synergistic catalytic effects and the composition as well as amount of co-catalysts was investigated. Moreover, the influence of different reaction conditions was studied in details. A high p-cresol conversion (>99%) and p-hydroxybenzaldehyde selectivity (83%) were obtained using only 1.125×10-5 mol T(p-CH3O)PPFeCl-Co(OAc)2 used under mild, optimized reaction conditions. A possible mechanism for the reaction was also proposed. This work would be meaningful and instructive for the further researches and applications of co-catalyst system on oxidation of cresols and could give some enlightenment on the selectively catalytic oxidation of the side-chain alkyls of aromatics.

关键词: Aerobic, Oxidation, Selectivity, Co-catalyst, Metalloporphyrin, Cresols

Abstract: A green and efficient method for the selective aerobic oxidation of p-cresol to p-hydroxybenzaldehyde catalyzed by co-catalysts between metalloporphyrins and metal salts was investigated and developed. The relationship between the synergistic catalytic effects and the composition as well as amount of co-catalysts was investigated. Moreover, the influence of different reaction conditions was studied in details. A high p-cresol conversion (>99%) and p-hydroxybenzaldehyde selectivity (83%) were obtained using only 1.125×10-5 mol T(p-CH3O)PPFeCl-Co(OAc)2 used under mild, optimized reaction conditions. A possible mechanism for the reaction was also proposed. This work would be meaningful and instructive for the further researches and applications of co-catalyst system on oxidation of cresols and could give some enlightenment on the selectively catalytic oxidation of the side-chain alkyls of aromatics.

Key words: Aerobic, Oxidation, Selectivity, Co-catalyst, Metalloporphyrin, Cresols