Complete kinetic model for esterification reaction of lauric acid with glycerol to synthesize glycerol monolaurate

doi:10.1016/j.cjche.2024.03.013

中国化学工程学报 ›› 2024, Vol. 70 ›› Issue (6): 211-221.DOI: 10.1016/j.cjche.2024.03.013

Complete kinetic model for esterification reaction of lauric acid with glycerol to synthesize glycerol monolaurate

Han-Qiao Hu¹, Yue Zhang¹, Ming Fan³, Yong Cai³, Guang-Wen Chu^1,2, Liang-Liang Zhang^1,2

1. Research Center of the Ministry of Education for High Gravity Engineering and Technology, Beijing University of Chemical Technology, Beijing 100029, China;
2. State Key Laboratory of Organic-Inorganic Composites, Beijing University of Chemical Technology, Beijing 100029, China;
3. Petrochemical Research Institute, China National Petroleum Corporation, Beijing 102206, China

收稿日期:2023-11-24 修回日期:2024-03-18 出版日期:2024-06-28 发布日期:2024-08-05
通讯作者: Liang-Liang Zhang,Tel.:+86 10 64443134;Fax:+86 10 64434784.E-mail:zhll@mail.buct.edu.cn
基金资助:
This work was financially supported by the National Research and Development Program of China (2021YFC3001100) and the National Natural Science Foundation of China (22288102).

Complete kinetic model for esterification reaction of lauric acid with glycerol to synthesize glycerol monolaurate

Han-Qiao Hu¹, Yue Zhang¹, Ming Fan³, Yong Cai³, Guang-Wen Chu^1,2, Liang-Liang Zhang^1,2

1. Research Center of the Ministry of Education for High Gravity Engineering and Technology, Beijing University of Chemical Technology, Beijing 100029, China;
2. State Key Laboratory of Organic-Inorganic Composites, Beijing University of Chemical Technology, Beijing 100029, China;
3. Petrochemical Research Institute, China National Petroleum Corporation, Beijing 102206, China

Received:2023-11-24 Revised:2024-03-18 Online:2024-06-28 Published:2024-08-05
Contact: Liang-Liang Zhang,Tel.:+86 10 64443134;Fax:+86 10 64434784.E-mail:zhll@mail.buct.edu.cn
Supported by:
This work was financially supported by the National Research and Development Program of China (2021YFC3001100) and the National Natural Science Foundation of China (22288102).

摘要/Abstract

摘要： Glycerol monolaurate (GML) is a widely used industrial chemical with excellent emulsification and antibacterial effect. The direct esterification of glycerol with lauric acid is the main method to synthesize GML. In this work, the kinetic process of direct esterification was systematically studied using p-toluenesulfonic acid as catalyst. A complete kinetic model of consecutive esterification reaction has been established, and the kinetic equation of acid catalysis was deduced. The isomerization reactions of GML and glycerol dilaurate were investigated. It was found that the reaction was an equilibrium reaction and the reaction rate was faster than the esterification reaction. The kinetic equations of the consecutive esterification reaction were obtained by experiments as k₁ = (276+92261X_cat)exp(-37720/RT) and k₂ = (80 +4413X_cat)exp(-32240/RT). The kinetic results are beneficial to the optimization of operating conditions and reactor design in GML production process.

关键词: Glycerol monolaurate, p-Toluenesulfonic acid, Esterification, Kinetics, Mass transfer

Abstract: Glycerol monolaurate (GML) is a widely used industrial chemical with excellent emulsification and antibacterial effect. The direct esterification of glycerol with lauric acid is the main method to synthesize GML. In this work, the kinetic process of direct esterification was systematically studied using p-toluenesulfonic acid as catalyst. A complete kinetic model of consecutive esterification reaction has been established, and the kinetic equation of acid catalysis was deduced. The isomerization reactions of GML and glycerol dilaurate were investigated. It was found that the reaction was an equilibrium reaction and the reaction rate was faster than the esterification reaction. The kinetic equations of the consecutive esterification reaction were obtained by experiments as k₁ = (276+92261X_cat)exp(-37720/RT) and k₂ = (80 +4413X_cat)exp(-32240/RT). The kinetic results are beneficial to the optimization of operating conditions and reactor design in GML production process.

Key words: Glycerol monolaurate, p-Toluenesulfonic acid, Esterification, Kinetics, Mass transfer

Han-Qiao Hu, Yue Zhang, Ming Fan, Yong Cai, Guang-Wen Chu, Liang-Liang Zhang. Complete kinetic model for esterification reaction of lauric acid with glycerol to synthesize glycerol monolaurate[J]. 中国化学工程学报, 2024, 70(6): 211-221.

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Complete kinetic model for esterification reaction of lauric acid with glycerol to synthesize glycerol monolaurate

Complete kinetic model for esterification reaction of lauric acid with glycerol to synthesize glycerol monolaurate

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