Smart membranes for biomedical applications

doi:10.1016/j.cjche.2022.06.006

Abstract

Abstract: Smart membranes with tunable permeability and selectivity have drawn widespread attention because of their unique biomimetic characteristics. Constructed by incorporating various stimuli-responsive materials into membrane substrates, smart membranes could self-adjust their physical/chemical properties (such as pore size and surface properties) in response to environmental signals such as temperature, pH, light, magnetic field, electric field, redox and specific ions/molecules. Such smart membranes show great prospects in biomedical applications ranging from controlled drug release to bioseparation and tissue engineering. In this review, three controlled release models realized by different designed smart membranes are emphatically introduced, and then smart membranes for biological separation and controlled cell culture are introduced and discussed respectively. At last, the existing challenges of smart membranes for biomedical applications are briefly summarized, and future research topics are suggested.

Key words: Membranes, Polymers, Smart materials, Controlled release, Bioseparation, Cell culture

摘要： Smart membranes with tunable permeability and selectivity have drawn widespread attention because of their unique biomimetic characteristics. Constructed by incorporating various stimuli-responsive materials into membrane substrates, smart membranes could self-adjust their physical/chemical properties (such as pore size and surface properties) in response to environmental signals such as temperature, pH, light, magnetic field, electric field, redox and specific ions/molecules. Such smart membranes show great prospects in biomedical applications ranging from controlled drug release to bioseparation and tissue engineering. In this review, three controlled release models realized by different designed smart membranes are emphatically introduced, and then smart membranes for biological separation and controlled cell culture are introduced and discussed respectively. At last, the existing challenges of smart membranes for biomedical applications are briefly summarized, and future research topics are suggested.

关键词: Membranes, Polymers, Smart materials, Controlled release, Bioseparation, Cell culture

Lin-Bing Zou, Jue-Ying Gong, Xiao-Jie Ju, Zhuang Liu, Wei Wang, Rui Xie, Liang-Yin Chu. Smart membranes for biomedical applications[J]. Chinese Journal of Chemical Engineering, 2022, 49(9): 34-45.

Lin-Bing Zou, Jue-Ying Gong, Xiao-Jie Ju, Zhuang Liu, Wei Wang, Rui Xie, Liang-Yin Chu. Smart membranes for biomedical applications[J]. 中国化学工程学报, 2022, 49(9): 34-45.

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