Chromatographic separation of 99Mo from 131I using amine-functionalized exchange resins

doi:10.1016/j.cjche.2025.07.004

摘要/Abstract

摘要： The current industrial-scale production of molybdenum-99 (⁹⁹Mo) and iodine-131 (¹³¹I) is heavily predicated on thermal neutron irradiation of LEU targets. In this route, ⁹⁹Mo and ¹³¹I are separated using a solid-phase extraction approach. The goal of this study was to develop and evaluate copolymeric beads that could be used to separate ⁹⁹Mo and ¹³¹I from their aqueous solutions. Different aminated styrene-divinyl benzene co-polymeric beads were successfully manufactured for this approach. The structural features of the synthesized copolymers were characterized. The resin frameworks were found to have homogeneous spherical shapes decorated with a very thin layer of amine moieties. The FT-IR peaks caused by N-H stretching and C-N bending vibrations show the successful functionalization of the resins' surfaces with amine moieties selective for the sorption of I^- over MoO₄^2- ions. Under various circumstances, the produced resins were assessed for sorption of ⁹⁹Mo and ¹³¹I from their aqueous solutions. They showed an enhanced sorption capability for I^- ions compared to MoO₄^2- ions and attained equilibrium in less than 20 min. Data declare that the sorption of MoO₄^2- and I^- ions onto synthesized resins was attained through an ion exchange process with Cl^- ions. In such interactions, one iodide ion (I^-) consumes only one active site from the resin surface, while two active sites must be exhausted to retain one MoO₄^2- ion onto the surface of the resins. The exchange interaction of both MoO₄^2- and I^- ions was an endothermic process. Further, the elution of ⁹⁹Mo and ¹³¹I radioisotopes loaded on synthesized resins was investigated using various eluents. Additional sets of individual and binary dynamic experiments were performed using columns packed with trimethylamine styrene divinyl benzene (TMA-PSDVB) and triethylamine styrene divinyl benzene (TEA-PSDVB) resins. The individual breakthrough sorption capacity of TMA-PSDVB and TEA-PSDVB resins had values of 381.6 and 352.6 mg·g^-1 for ¹³¹I and values of 134.7 and 117.2 mg·g^-1 for ⁹⁹Mo isotopes, respectively. Furthermore, TMA-PSDVB resin exhibited breakthrough sorption capacity for ⁹⁹Mo and ¹³¹I, in the binary system, amounting to 123.7 and 331.6 mg·g^-1 with elution percentages reaching 75.4% and 12.1%, respectively. These findings demonstrate that Mo(VI) ions were efficiently separated from I(I) ions. Finally, the reported aminated polymeric resins may be regarded as promising solid phases for the separation and recovery of Mo(VI) and I(I).

关键词: Chromatographic, Separation, Exchange resins, ⁹⁹Mo, ¹³¹I

Abstract: The current industrial-scale production of molybdenum-99 (⁹⁹Mo) and iodine-131 (¹³¹I) is heavily predicated on thermal neutron irradiation of LEU targets. In this route, ⁹⁹Mo and ¹³¹I are separated using a solid-phase extraction approach. The goal of this study was to develop and evaluate copolymeric beads that could be used to separate ⁹⁹Mo and ¹³¹I from their aqueous solutions. Different aminated styrene-divinyl benzene co-polymeric beads were successfully manufactured for this approach. The structural features of the synthesized copolymers were characterized. The resin frameworks were found to have homogeneous spherical shapes decorated with a very thin layer of amine moieties. The FT-IR peaks caused by N-H stretching and C-N bending vibrations show the successful functionalization of the resins' surfaces with amine moieties selective for the sorption of I^- over MoO₄^2- ions. Under various circumstances, the produced resins were assessed for sorption of ⁹⁹Mo and ¹³¹I from their aqueous solutions. They showed an enhanced sorption capability for I^- ions compared to MoO₄^2- ions and attained equilibrium in less than 20 min. Data declare that the sorption of MoO₄^2- and I^- ions onto synthesized resins was attained through an ion exchange process with Cl^- ions. In such interactions, one iodide ion (I^-) consumes only one active site from the resin surface, while two active sites must be exhausted to retain one MoO₄^2- ion onto the surface of the resins. The exchange interaction of both MoO₄^2- and I^- ions was an endothermic process. Further, the elution of ⁹⁹Mo and ¹³¹I radioisotopes loaded on synthesized resins was investigated using various eluents. Additional sets of individual and binary dynamic experiments were performed using columns packed with trimethylamine styrene divinyl benzene (TMA-PSDVB) and triethylamine styrene divinyl benzene (TEA-PSDVB) resins. The individual breakthrough sorption capacity of TMA-PSDVB and TEA-PSDVB resins had values of 381.6 and 352.6 mg·g^-1 for ¹³¹I and values of 134.7 and 117.2 mg·g^-1 for ⁹⁹Mo isotopes, respectively. Furthermore, TMA-PSDVB resin exhibited breakthrough sorption capacity for ⁹⁹Mo and ¹³¹I, in the binary system, amounting to 123.7 and 331.6 mg·g^-1 with elution percentages reaching 75.4% and 12.1%, respectively. These findings demonstrate that Mo(VI) ions were efficiently separated from I(I) ions. Finally, the reported aminated polymeric resins may be regarded as promising solid phases for the separation and recovery of Mo(VI) and I(I).

Key words: Chromatographic, Separation, Exchange resins, ⁹⁹Mo, ¹³¹I

Reda R. Sheha, Dalia M. Dorrah, G. M. El-Subruiti, M. S. Masoud, Saber I. Moussa. Chromatographic separation of ⁹⁹Mo from ¹³¹I using amine-functionalized exchange resins[J]. 中国化学工程学报, 2025, 88(12): 348-358.

Reda R. Sheha, Dalia M. Dorrah, G. M. El-Subruiti, M. S. Masoud, Saber I. Moussa. Chromatographic separation of ⁹⁹Mo from ¹³¹I using amine-functionalized exchange resins[J]. Chinese Journal of Chemical Engineering, 2025, 88(12): 348-358.

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Chromatographic separation of ⁹⁹Mo from ¹³¹I using amine-functionalized exchange resins

Chromatographic separation of ⁹⁹Mo from ¹³¹I using amine-functionalized exchange resins

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