Separation of α-Tocopherol with a Two-Feed Simulated Moving Bed

Chinese Journal of Chemical Engineering ›› 2012, Vol. 20 ›› Issue (4): 673-678.

Separation of α-Tocopherol with a Two-Feed Simulated Moving Bed

危凤, 沈波, 陈明杰, 周先波, 赵迎宪

Ningbo Institute of Technology, Zhejiang University, Ningbo 315100, China

收稿日期:2011-03-22 修回日期:2011-06-09 出版日期:2012-08-28 发布日期:2012-09-15
通讯作者: WEI Feng, E-mail:weifeng@nit.net.cn
基金资助:
Supported by the Natural Science Foundation of Ningbo,China (2009A610153);Analysis & Measurement Foundation ofZhejiang (2009F70066);Education Bureau of Ningbo,China (Jd090222)

Separation of α-Tocopherol with a Two-Feed Simulated Moving Bed

WEI Feng, SHEN Bo, CHEN Mingjie, ZHOU Xianbo, ZHAO Yingxian

Ningbo Institute of Technology, Zhejiang University, Ningbo 315100, China

Received:2011-03-22 Revised:2011-06-09 Online:2012-08-28 Published:2012-09-15
Supported by:
Supported by the Natural Science Foundation of Ningbo,China (2009A610153);Analysis & Measurement Foundation ofZhejiang (2009F70066);Education Bureau of Ningbo,China (Jd090222)

摘要/Abstract

摘要： A two-feed simulated moving bed(SMB) was proposed to utilize the stationary phase more effectively.Zone I is disconnected with zone Ⅱ and zone Ⅲ is disconnected with zone IV.Two feeds are added to zones Ⅰ and Ⅲ,while two desorbents are added to zones Ⅱ and IV separately.The investigation on the movement of concentra-tion bands indicated that the tail of the strong retained solute and the front of the weak retained solute were eluted from zones Ⅰ and Ⅲ orderly,so the streams from zones Ⅰ and Ⅲ could be cut into different fractions to give the products with high purity.The two-feed SMB was used to separate α-tocopherol from its homologue mixture successfully,and could double the productivity if both feeds were identical to the feed in the conventional four-zone SMB.The solvent consumption could be reduced by reusing the middle fraction without solutes.

关键词: simulated moving bed, two-feed, tocopherol

Abstract: A two-feed simulated moving bed(SMB) was proposed to utilize the stationary phase more effectively.Zone I is disconnected with zone Ⅱ and zone Ⅲ is disconnected with zone IV.Two feeds are added to zones Ⅰ and Ⅲ,while two desorbents are added to zones Ⅱ and IV separately.The investigation on the movement of concentra-tion bands indicated that the tail of the strong retained solute and the front of the weak retained solute were eluted from zones Ⅰ and Ⅲ orderly,so the streams from zones Ⅰ and Ⅲ could be cut into different fractions to give the products with high purity.The two-feed SMB was used to separate α-tocopherol from its homologue mixture successfully,and could double the productivity if both feeds were identical to the feed in the conventional four-zone SMB.The solvent consumption could be reduced by reusing the middle fraction without solutes.

Key words: simulated moving bed, two-feed, tocopherol

危凤, 沈波, 陈明杰, 周先波, 赵迎宪. Separation of α-Tocopherol with a Two-Feed Simulated Moving Bed[J]. Chinese Journal of Chemical Engineering, 2012, 20(4): 673-678.

WEI Feng, SHEN Bo, CHEN Mingjie, ZHOU Xianbo, ZHAO Yingxian. Separation of α-Tocopherol with a Two-Feed Simulated Moving Bed[J]. Chin.J.Chem.Eng., 2012, 20(4): 673-678.

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Separation of α-Tocopherol with a Two-Feed Simulated Moving Bed

Separation of α-Tocopherol with a Two-Feed Simulated Moving Bed

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