A convenient method for the determination of molecular weight cut-off of ultrafiltration membranes

doi:10.1016/j.cjche.2016.06.014

›› 2017, Vol. 25 ›› Issue (1): 62-67.DOI: 10.1016/j.cjche.2016.06.014

• Separation Science and Engineering • 上一篇下一篇

A convenient method for the determination of molecular weight cut-off of ultrafiltration membranes

Cunyu Li^1,2, Yun Ma¹, Hongyang Li¹, Guoping Peng^1,2

1 Pharmacy College, Nanjing University of Chinese Medicine, Nanjing 210023, China;
2 Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, Nanjing 210023, China

收稿日期:2016-04-15 修回日期:2016-06-29 出版日期:2017-01-28 发布日期:2017-02-15
通讯作者: Guoping Peng,E-mail address:guopingpeng@126.com
基金资助:
Supported by the National Natural Science Foundation of China (No. 81503258, No. 81373980), Youth Natural Science Foundation of Jiangsu Province (No. BK20151005), Science and Technology Project of Jiangsu Traditional Chinese Medicine Administration (No. YB2015009).

A convenient method for the determination of molecular weight cut-off of ultrafiltration membranes

Cunyu Li^1,2, Yun Ma¹, Hongyang Li¹, Guoping Peng^1,2

1 Pharmacy College, Nanjing University of Chinese Medicine, Nanjing 210023, China;
2 Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, Nanjing 210023, China

Received:2016-04-15 Revised:2016-06-29 Online:2017-01-28 Published:2017-02-15
Supported by:
Supported by the National Natural Science Foundation of China (No. 81503258, No. 81373980), Youth Natural Science Foundation of Jiangsu Province (No. BK20151005), Science and Technology Project of Jiangsu Traditional Chinese Medicine Administration (No. YB2015009).

摘要/Abstract

摘要： With the rapid increase of water contamination, membrane separation technology and their corresponding molecular weight cut-off (MWCO) evaluation method become more necessary. In this study, Panax notoginseng saponins was used as a new standard marker to determinate ultrafiltration (UF) membrane MWCOs, series of Millipore membranes were selected as control group to analyze and calculate the relationship between retention rate and MWCOs with exponential or logarithmic equation. A new and convenient method was provided for determining the membrane MWCO by modeling analysis retention rate with MWCOs, and the regression coefficients ≥0.990. The feasibility and practicability of established method was verified by different manufactures' membrane and dextrans. In the detection progress, as the main ingredient of Panax notoginseng saponins, Notoginsenoside R₁, Ginsenoside Rg₁, Ginsenoside Rb₁ and Ginsenoside Rd with different surface activity, the MWCO range of UF membranes can be divided into two zones mainly due to the retention rate difference among Notoginsenoside R₁, Ginsenoside Rg₁, Ginsenoside Rb₁ and Ginsenoside Rd. Zone I, 1000-10000; and Zone II, 10000-100000. Thus, the new method would be helpful to improve the applicability of UF membrane in separation technology.

关键词: Ultrafiltration membrane, Molecular weight cut-off

Abstract: With the rapid increase of water contamination, membrane separation technology and their corresponding molecular weight cut-off (MWCO) evaluation method become more necessary. In this study, Panax notoginseng saponins was used as a new standard marker to determinate ultrafiltration (UF) membrane MWCOs, series of Millipore membranes were selected as control group to analyze and calculate the relationship between retention rate and MWCOs with exponential or logarithmic equation. A new and convenient method was provided for determining the membrane MWCO by modeling analysis retention rate with MWCOs, and the regression coefficients ≥0.990. The feasibility and practicability of established method was verified by different manufactures' membrane and dextrans. In the detection progress, as the main ingredient of Panax notoginseng saponins, Notoginsenoside R₁, Ginsenoside Rg₁, Ginsenoside Rb₁ and Ginsenoside Rd with different surface activity, the MWCO range of UF membranes can be divided into two zones mainly due to the retention rate difference among Notoginsenoside R₁, Ginsenoside Rg₁, Ginsenoside Rb₁ and Ginsenoside Rd. Zone I, 1000-10000; and Zone II, 10000-100000. Thus, the new method would be helpful to improve the applicability of UF membrane in separation technology.

Key words: Ultrafiltration membrane, Molecular weight cut-off

Cunyu Li, Yun Ma, Hongyang Li, Guoping Peng. A convenient method for the determination of molecular weight cut-off of ultrafiltration membranes[J]. , 2017, 25(1): 62-67.

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A convenient method for the determination of molecular weight cut-off of ultrafiltration membranes

A convenient method for the determination of molecular weight cut-off of ultrafiltration membranes

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