SCI和EI收录∣中国化工学会会刊

›› 2009, Vol. 17 ›› Issue (2): 324-329.

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Improvement of Hydrophilicity and Blood Compatibility on Polyethersulfone Membrane by Blending Sulfonated Polyethersulfone

王海涛1, 杨刘2, 赵学辉1, 于湉1, 杜启云1   

  1. 1. The Key Lab of Hollow Fiber Membrane Materials and Membrane Process of Ministry of Education, Tianjin Polytechnic University, Tianjin 300160, China;
    2. Department of Bio-medical Engineering, Tianjin Polytechnic University, Tianjin 300160, China
  • 收稿日期:2008-08-28 修回日期:2008-12-19 出版日期:2009-04-28 发布日期:2009-04-28
  • 通讯作者: WANG Haitao,E-mail:whaitao134@163.com
  • 基金资助:
    Supported by the Special Fund for International Cooperation Projects of China (2005DFA50160)

Improvement of Hydrophilicity and Blood Compatibility on Polyethersulfone Membrane by Blending Sulfonated Polyethersulfone

WANG Haitao1, YANG Liu2, ZHAO Xuehui1, YU Tian1, DU Qiyun1   

  1. 1. The Key Lab of Hollow Fiber Membrane Materials and Membrane Process of Ministry of Education, Tianjin Polytechnic University, Tianjin 300160, China;
    2. Department of Bio-medical Engineering, Tianjin Polytechnic University, Tianjin 300160, China
  • Received:2008-08-28 Revised:2008-12-19 Online:2009-04-28 Published:2009-04-28
  • Supported by:
    Supported by the Special Fund for International Cooperation Projects of China (2005DFA50160)

摘要: Polyethersulfone(PES) is widely used as biomaterials due to its thermal stability,mechanical strength,and chemical inertness.Nevertheless,their blood compatibility is still not adequate for hemodialysis and blood purification.In this study,the sulfonated polyethersulfone(SPES) was synthesized through an electrophilic substitution reaction,and PES/SPES blending membranes were prepared.The characterization of the SPES was studied by FTIR.The water adsorption and water contact angle experiments show that the hydrophilicity of PES/SPES blend membrane was improved as for the sulfonate group existing in the SPES.Moreover,PES/SPES blend membrane could effectively reduce bovine serum albumin adsorption and prolong the blood coagulation time compared with the PES membrane,thereby improving blood compatibility.

关键词: sulfonated polyethersulfone, polyethersulfone, hydrophilicity, blood compatibility, blending

Abstract: Polyethersulfone(PES) is widely used as biomaterials due to its thermal stability,mechanical strength,and chemical inertness.Nevertheless,their blood compatibility is still not adequate for hemodialysis and blood purification.In this study,the sulfonated polyethersulfone(SPES) was synthesized through an electrophilic substitution reaction,and PES/SPES blending membranes were prepared.The characterization of the SPES was studied by FTIR.The water adsorption and water contact angle experiments show that the hydrophilicity of PES/SPES blend membrane was improved as for the sulfonate group existing in the SPES.Moreover,PES/SPES blend membrane could effectively reduce bovine serum albumin adsorption and prolong the blood coagulation time compared with the PES membrane,thereby improving blood compatibility.

Key words: sulfonated polyethersulfone, polyethersulfone, hydrophilicity, blood compatibility, blending