Improvement of Hydrophilicity and Blood Compatibility on Polyethersulfone Membrane by Blending Sulfonated Polyethersulfone

›› 2009, Vol. 17 ›› Issue (2): 324-329.

Improvement of Hydrophilicity and Blood Compatibility on Polyethersulfone Membrane by Blending Sulfonated Polyethersulfone

王海涛¹, 杨刘², 赵学辉¹, 于湉¹, 杜启云¹

1. The Key Lab of Hollow Fiber Membrane Materials and Membrane Process of Ministry of Education, Tianjin Polytechnic University, Tianjin 300160, China;
2. Department of Bio-medical Engineering, Tianjin Polytechnic University, Tianjin 300160, China

收稿日期:2008-08-28 修回日期:2008-12-19 出版日期:2009-04-28 发布日期:2009-04-28
通讯作者: WANG Haitao,E-mail:whaitao134@163.com
基金资助:
Supported by the Special Fund for International Cooperation Projects of China (2005DFA50160)

Improvement of Hydrophilicity and Blood Compatibility on Polyethersulfone Membrane by Blending Sulfonated Polyethersulfone

WANG Haitao¹, YANG Liu², ZHAO Xuehui¹, YU Tian¹, DU Qiyun¹

1. The Key Lab of Hollow Fiber Membrane Materials and Membrane Process of Ministry of Education, Tianjin Polytechnic University, Tianjin 300160, China;
2. Department of Bio-medical Engineering, Tianjin Polytechnic University, Tianjin 300160, China

Received:2008-08-28 Revised:2008-12-19 Online:2009-04-28 Published:2009-04-28
Supported by:
Supported by the Special Fund for International Cooperation Projects of China (2005DFA50160)

摘要/Abstract

摘要： Polyethersulfone(PES) is widely used as biomaterials due to its thermal stability,mechanical strength,and chemical inertness.Nevertheless,their blood compatibility is still not adequate for hemodialysis and blood purification.In this study,the sulfonated polyethersulfone(SPES) was synthesized through an electrophilic substitution reaction,and PES/SPES blending membranes were prepared.The characterization of the SPES was studied by FTIR.The water adsorption and water contact angle experiments show that the hydrophilicity of PES/SPES blend membrane was improved as for the sulfonate group existing in the SPES.Moreover,PES/SPES blend membrane could effectively reduce bovine serum albumin adsorption and prolong the blood coagulation time compared with the PES membrane,thereby improving blood compatibility.

关键词: sulfonated polyethersulfone, polyethersulfone, hydrophilicity, blood compatibility, blending

Abstract: Polyethersulfone(PES) is widely used as biomaterials due to its thermal stability,mechanical strength,and chemical inertness.Nevertheless,their blood compatibility is still not adequate for hemodialysis and blood purification.In this study,the sulfonated polyethersulfone(SPES) was synthesized through an electrophilic substitution reaction,and PES/SPES blending membranes were prepared.The characterization of the SPES was studied by FTIR.The water adsorption and water contact angle experiments show that the hydrophilicity of PES/SPES blend membrane was improved as for the sulfonate group existing in the SPES.Moreover,PES/SPES blend membrane could effectively reduce bovine serum albumin adsorption and prolong the blood coagulation time compared with the PES membrane,thereby improving blood compatibility.

Key words: sulfonated polyethersulfone, polyethersulfone, hydrophilicity, blood compatibility, blending

王海涛, 杨刘, 赵学辉, 于湉, 杜启云. Improvement of Hydrophilicity and Blood Compatibility on Polyethersulfone Membrane by Blending Sulfonated Polyethersulfone[J]. , 2009, 17(2): 324-329.

WANG Haitao, YANG Liu, ZHAO Xuehui, YU Tian, DU Qiyun. Improvement of Hydrophilicity and Blood Compatibility on Polyethersulfone Membrane by Blending Sulfonated Polyethersulfone[J]. , 2009, 17(2): 324-329.

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Improvement of Hydrophilicity and Blood Compatibility on Polyethersulfone Membrane by Blending Sulfonated Polyethersulfone

Improvement of Hydrophilicity and Blood Compatibility on Polyethersulfone Membrane by Blending Sulfonated Polyethersulfone

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